With a pair of wins already in their pocket thanks to late heroics, the San Diego Padres couldn’t find the late magic a third time as they lost 3-2 in another one-run game against the San Francisco Giants on Thursday afternoon at Oracle Park.

Manny Machado staked the Padres (35-26) to an early two-run lead on his 350th career home run, becoming the 102nd player in MLB history to accomplish the feat.

But San Francisco’s (35-28) southpaw starter Robbie Ray went seven innings to earn his eighth win of the season, allowing four hits and the two runs to go with one walk and a season-high matching nine strikeouts. He’s thrown for nine K’s in three of his last five starts.

Machado and Gavin Sheets were aboard with singles in the ninth and one out against Giants closer Camilo Doval, then advanced to second and third on a ground out. But the fire-throwing Doval threw four straight 99.7-plus MPH pitches before getting the strikeout with a low slider for his eighth save.

Early on the Padres continued to find two-out success in the third inning, when Luis Arraez singled with two down to set up Machado. On the third pitch of the at bat, Machado crushed a middle-middle knuckle curve out to left field for his eighth home run of the season.

Machado is the 11th player to have played for the Padres franchise who has hit for at least 350 career home runs. Nelson Cruz, who donned the brown and gold in his final season in the Majors in 2023, is the previous most recent to do so.

Since a 17-game stretch from May 12 to 31 without a multiple-RBI game where he drove in five total, Machado has now had three games out of the past six with two RBIs.

Dylan Cease danced on a razor’s edge early in his staff-leading 13th start, escaping a one-out, men on second and third situation in the first inning. The Giants made the San Diego starter pay in the third by scoring their first three runs and sending him to his fifth loss.

A pair of one-out walks followed by a Matt Chapman single loaded the bases. Then Willy Adames brought one home with a sacrifice fly and Dominic Smith hit a ground-rule double to give the hosts a 3-2 lead.

Cease dialed in afterwards, getting the Giants in order in the fourth and the fifth to make it through five full innings for the fifth time in his last six starts. He allowed five hits and the three runs, with seven strikeouts but also allowed three walks — his first multi-freebie start May 7 at the Yankees.

After Ray allowed the Machado home run, the lefty retired 11 in a row before Jose Iglesias hit a sharp liner off the base of the wall in left center. Jerar Encarnacion fielded the ball clearly and delivered it on a line to Tyler Fitzgerald at second for the tag, as Iglesias attempted to take the double standing up.

Ray retired San Diego in order in five of his seven innings.

The Padres also had an opportunity in the eighth when Brandon Lockridge led off with a single and took second on a wild pitch by Randy Rondríguez, but Fernando Tatis Jr. had a liner to center die at the warning track and Rodr íguez got a strikeout to end the threat.

David Morgan made the longest appearance of his Majors career, allowing one hit and a walk to go with three strikeouts in two innings. Yuki Matsui pitched an unblemished eighth inning and had a strikeout.

Xander Bogaerts did not start, with shoulder soreness announced as the reason after exiting Wednesday’s game in the sixth inning. Additionally, Arraez was replaced in the bottom of the sixth by Wade.

Having opened their stretch of ten straight games against opponents above the .500-mark (Arizona, who San Diego travels to face on June 13 through 15, began the day with a 31-31 record) with a 2-2 split, up next for the Padres is the Milwaukee Brewers.

Game one will feature Randy Vásquez (3-4, 3.99 ERA) getting the nod for the Brown and Gold against right-hander Chad Patrick (3-4, 2.97 ERA). First pitch from American Family Field is scheduled for 5:10 p.m.