After being recalled from Triple-A Worcester on April 23, Tolle made 26 starts for the Red Sox, posting a 3.03 ERA, the fifth-lowest mark among American League rookie starters and seventh-lowest in baseball. Tolle also finished in the top five among American League rookie starters in strikeouts per nine innings (10.35, 3rd), walks per nine innings (2.42, 4th), home runs per nine innings (0.91, 4th), WHIP (1.10, T-2nd), fielding independent pitching (3.04, 1st) and fWAR (4.1, 2nd).