A series opener between the San Francisco Giants (44-37) and Chicago White Sox (26-55) is on deck Friday at 7:40 p.m. ET, at Rate Field.
The Giants are favored away from home (-168) versus the White Sox (+141). The matchup on the mound for this contest is set with the San Francisco Giants looking to Landen Roupp (5-5), and Aaron Civale (1-4) getting the nod for the Chicago White Sox.
The Giants lost 12-5 against the Marlins yesterday, with Hayden Birdsong taking the loss. He threw four innings, giving up seven earned runs on four hits while striking out one. Rafael Devers went 3 for 4 with a double, a home run and two RBIs to lead the Giants offensively.
The White Sox took down the Diamondbacks 7-3 Wednesday. Lenyn Sosa led the way offensively after going 3 for 4 with two home runs and four RBIs, and Sean Burke got the win, throwing five innings without giving up an earned run on five hits, while striking out seven.
Prepare for the Giants vs. White Sox with everything you need to know before Friday’s game, including viewing options.
San Francisco Giants vs. Chicago White Sox odds, line and spread
MLB odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 9:16 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Favorite: Giants (-168, bet $168 to win $100)Underdog: White Sox (+141, bet $100 to win $141)Over/under: 8.5Giants vs. White Sox: Game time and live stream infoGame day: Friday, June 27, 2025Game time: 7:40 p.m. ETLocation: Chicago, IllinoisStadium: Rate FieldTV channel: CHSN and NBCS-BALive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Watch Giants vs. White Sox on Fubo!
Giants stats and trendsGiants betting recordsThe Giants have won 29, or 55.8%, of the 52 games they’ve played as favorites this season.San Francisco is 7-7 this season when entering a game favored by -168 or more on the moneyline.The oddsmakers’ moneyline implies a 62.7% chance of a victory for the Giants.So far this season, San Francisco and its opponents have hit the over in 37 of 81 games with a total.The Giants are 35-46-0 ATS in their 81 games with a spread this season.Landen Roupp (Giants probable starter)Roupp (5-5 with a 3.79 ERA and 70 strikeouts in 76 2/3 innings pitched) makes the start for the Giants, his 16th of the season.In his last outing on Saturday against the Boston Red Sox, the right-hander threw six scoreless innings while surrendering three hits.In 15 games this season, the 26-year-old has amassed an ERA of 3.79, with 8.3 strikeouts per nine innings. Opponents are hitting .260 against him.Roupp is trying to pick up his eighth quality start of the season in this outing.Roupp has pitched five or more innings in a game 10 times this year heading into this matchup.In four of his 15 total appearances this season he has not given up an earned run.He will take the mound against a White Sox team that is batting .220 as a unit (30th in MLB). It is also slugging a collective .345 (29th in MLB) with 64 total home runs (28th in MLB).Giants batting statsThe Giants have hit 79 homers this season, which ranks 22nd in the league.The offense for San Francisco has a slugging percentage of .375 this season, 25th in MLB.The Giants have a team batting average of .231 this season, which ranks 24th among MLB teams.San Francisco has scored the 15th-most runs in the majors this season with 344 (4.2 per game).The Giants have an OBP of .312 this season, which ranks 21st in MLB.San Francisco ranks 18th with an average of 8.4 strikeouts per game.White Sox stats and trendsWhite Sox betting recordsThe White Sox have been chosen as underdogs in 81 games this year and have walked away with the win 26 times (32.1%) in those games.Chicago has a mark of 15-37 in contests where bookmakers favor it by +141 or worse on the moneyline.The moneyline set for this matchup implies the White Sox have a 41.5% chance of walking away with the win.Chicago and its opponents have hit the over in 36 of its 81 games with a total set by oddsmakers this season.The White Sox are 46-35-0 against the spread in their 81 games with a line set by sportsbooks this season.Aaron Civale (White Sox probable starter)Civale (1-4) takes the mound first for the White Sox in his eighth start of the season. He has a 5.03 ERA in 34 2/3 innings pitched, with 25 strikeouts.In his most recent appearance on Saturday against the Toronto Blue Jays, the right-hander threw seven innings, giving up five earned runs while surrendering nine hits.In seven games this season, the 30-year-old has an ERA of 5.03, with 6.6 strikeouts per nine innings. Opponents are batting .286 against him.Civale has not registered a quality start so far this season.Civale is seeking his third straight appearance lasting five or more innings. He averages 4.9 innings per start.He has not had an appearance so far in 2025 where he did not give up at least one earned run.The opposing Giants offense has the 25th-ranked slugging percentage (.375) and ranks 22nd in home runs hit (79) in all of MLB. They have a collective .231 batting average, and are 26th in the league with 614 total hits and 15th in MLB play scoring 344 runs.White Sox batting statsThe White Sox are third-worst in MLB play with 64 home runs.So far this season, Chicago is slugging .345, the second-lowest percentage in baseball.The White Sox have the worst batting average in the majors (.220).Chicago scores the third-fewest runs in baseball (280 total, 3.5 per game).The White Sox are 27th in MLB with a .293 on-base percentage.