On Wednesday, the Baltimore Orioles (60-72) are hosting the Boston Red Sox (73-60), at 6:35 p.m. ET, in the third game of a four-game set.

As the favorite, the Red Sox (-154 moneyline odds) take the field at the Orioles (+130). The scheduled starters are Brayan Bello (10-6) for the Boston Red Sox, and Dietrich Enns (1-2) for the Baltimore Orioles.

These teams meet again after the Red Sox took down the Orioles 5-0 yesterday. Lucas Giolito picked up the win for the Red Sox (8.0 IP, 0 R, 4 H, 8 K), and David Hamilton led the way offensively (2 for 3 with a double, a home run and three RBIs). Kyle Bradish (6.0 IP, 2 R, 4 H, 10 K) took the loss for the Orioles.

Get ready for the Red Sox vs. Orioles with everything you need to know about Wednesday’s game, including viewing options.

Boston Red Sox vs. Baltimore Orioles odds, line and spread

MLB odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 12:16 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Favorite: Red Sox (-154, bet $154 to win $100)Underdog: Orioles (+130, bet $100 to win $130)Over/under: 9Red Sox vs. Orioles: Game time and live stream infoGame day: Wednesday, August 27, 2025Game time: 6:35 p.m. ETLocation: Baltimore, MarylandStadium: Oriole Park at Camden YardsTV channel: MASN and NESNLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)

Watch Red Sox vs. Orioles on Fubo!

Red Sox stats and trendsRed Sox betting recordsThe Red Sox have been favorites in 79 games this season and won 47 (59.5%) of those contests.Boston has a record of 16-10, a 61.5% win rate, when favored by -154 or more by oddsmakers this season.The sportsbooks’ moneyline implies a 60.6% chance of a victory for the Red Sox.Games involving Boston have gone over the total set by bookmakers in 65 of 132 chances this season.The Red Sox are 70-62-0 against the spread in their 132 chances this season.Brayan Bello (Red Sox probable starter)Bello (10-6) gets the starting nod for the Red Sox in his 23rd start of the season. He’s put together a 3.07 ERA in 135 2/3 innings pitched, with 102 strikeouts.The right-hander last pitched on Friday against the New York Yankees, when he went seven scoreless innings while giving up three hits.The 26-year-old has amassed an ERA of 3.07, with 6.8 strikeouts per nine innings, in 23 games this season. Opponents are hitting .239 against him.Bello is looking to register his third quality start in a row in this outing.Bello is seeking his 16th straight appearance lasting five or more innings. He averages 5.9 frames per appearance on the hill.He has held his opponents without an earned run in four of his 23 outings this season.He will face off against an Orioles squad that is batting .241 as a unit (22nd in MLB). It is also slugging a collective .403 (14th in MLB) with 159 total home runs (11th in MLB).Head-to-head against the Orioles this season, Bello has pitched four innings, giving up two earned runs on six hits while striking out seven.The 26-year-old ranks 15th in ERA (3.07), 28th in WHIP (1.222), and 46th in K/9 (6.8) among qualifying pitchers in MLB play this season.Red Sox batting statsThe Red Sox rank 11th in Major League Baseball with 159 home runs.Hitters for Boston rank seventh in the majors with a combined .425 team slugging percentage.The Red Sox rank fourth in MLB with a .253 team batting average.Boston has scored 662 runs this season, which ranks fourth in MLB.The Red Sox have an OBP of .324 this season, which ranks seventh in MLB.Boston is one of the least-disciplined teams at the plate this season, ranking 27th with an average of 8.8 strikeouts per game.Orioles stats and trendsOrioles betting recordsThe Orioles have won in 32, or 45.7%, of the 70 contests they have been named as odds-on underdogs this year.This year, Baltimore has won five of 18 games when listed as at least +130 or worse on the moneyline.The moneyline set for this matchup implies the Orioles have a 43.5% chance of walking away with the win.Baltimore and its opponents have gone over the total this season in 56 of its 132 opportunities.In 132 games with a line this season, the Orioles have a mark of 61-71-0 against the spread.Dietrich Enns (Orioles probable starter)Enns (1-2) gets the starting nod for the Orioles, his third this season.In his most recent appearance — in relief on Saturday — the left-hander threw two innings against the Houston Astros, allowing two earned runs while surrendering three hits.Over his 15 games this season, opposing hitters have a collective batting average of .303 against him. He has a 4.97 ERA and averages 9.9 strikeouts per nine innings.Enns enters this matchup with one outing of five or more innings pitched this year.He has had nine appearances this season in which he did not surrender an earned run.He meets a Red Sox offense that ranks fourth in the league with 662 total runs scored while batting .253 as a unit. His opponent has a collective .425 slugging percentage (seventh in MLB action) and has hit a total of 159 home runs (11th in the league).Head-to-head against the Red Sox this season, Enns has pitched one inning, giving up one earned run on one hit while striking out one.Orioles batting statsThe Orioles rank 11th in MLB action with 159 total home runs.So far this season, Baltimore is 14th in the majors, slugging .403.The Orioles are 22nd in the majors with a .241 batting average.Baltimore scores the 18th-most runs in baseball (570 total, 4.3 per game).The Orioles are 24th in baseball with an on-base percentage of .306.

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