A series opener between the San Diego Padres (76-61) and Baltimore Orioles (61-76) is scheduled for Monday at 6:40 p.m. ET, at PETCO Park.
The Orioles are an underdog away (+137) versus the Padres (-162). The matchup on the mound for this contest is set with the San Diego Padres looking to Dylan Cease (6-11), and Kyle Bradish (0-1) answering the bell for the Baltimore Orioles.
The Padres lost 7-2 against the Twins yesterday, with Kyle Hart taking the loss. He threw 1 1/3 innings, giving up three earned runs on one hit while striking out one. Bryce Johnson went 1 for 1 with an RBI to lead the Padres offensively.
The Orioles were defeated by the Giants 13-2 yesterday. Jackson Holliday went 1 for 2 with a double and an RBI in the defeat, while Tomoyuki Sugano took the loss on the mound, throwing 3 1/3 innings, giving up seven earned runs on 10 hits while striking out four.
Before watching this Padres vs. Orioles matchup, here is everything you need to know about Monday’s action on the diamond, including viewing options.
San Diego Padres vs. Baltimore Orioles odds, line and spread
MLB odds courtesy of BetMGM Sportsbook. Odds updated Monday at 6:23 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Favorite: Padres (-162, bet $162 to win $100)Underdog: Orioles (+137, bet $100 to win $137)Over/under: 7.5Padres vs. Orioles: Game time and live stream infoGame day: Monday, September 1, 2025Game time: 6:40 p.m. ETLocation: San Diego, CaliforniaStadium: PETCO ParkTV channel: SDPA and MASN2Live stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Watch Padres vs. Orioles on Fubo!
Padres stats and trendsPadres betting recordsThe Padres have won 44, or 61.1%, of the 72 games they’ve played as favorites this season.San Diego has a record of 16-9 in games when sportsbooks favor them by at least -162 on the moneyline.The oddsmakers’ moneyline implies a 61.8% chance of a victory for the Padres.San Diego’s games have gone over the total in 59 of its 137 chances.In 137 games with a spread this season, the Padres are 76-61-0 ATS.Dylan Cease (Padres probable starter)Cease (6-11) takes the mound for the Padres in his 28th start of the season. He has a 4.82 ERA in 142 2/3 innings pitched, with 183 strikeouts.In his last appearance on Wednesday against the Seattle Mariners, the right-hander tossed 4 1/3 innings, allowing four earned runs while surrendering four hits.The 29-year-old has an ERA of 4.82, with 11.6 strikeouts per nine innings, in 27 games this season. Opposing hitters have a .237 batting average against him.Cease has seven quality starts under his belt this season.Cease enters the game with 18 outings of five or more innings pitched this year.In three of his appearances this season he did not surrender an earned run.He will face off against an Orioles offense that ranks 21st in MLB with 1113 total hits (on a .242 batting average). The squad also slugs a collective .405 (13th in MLB) with 164 total home runs (12th in MLB).This season, the 29-year-old ranks 47th in ERA (4.82), 47th in WHIP (1.331), and second in K/9 (11.6) among qualifying pitchers.Padres batting statsThe Padres have hit just 119 homers this season, which ranks 29th in the league.Hitters for San Diego have combined for a team rank of 24th in the majors with a .386 team slugging percentage.The Padres’ .252 batting average is among the best in baseball, ranking fifth in MLB.San Diego has scored the 20th-most runs in the majors this season with 582 (4.2 per game).The Padres have an OBP of .322 this season, which ranks ninth in MLB.San Diego ranks third in MLB in strikeouts per game with an average of seven whiffs per contest.Orioles stats and trendsOrioles betting recordsThe Orioles have won in 32, or 43.2%, of the 74 contests they have been named as odds-on underdogs this year.This season, Baltimore has been victorious five times in 16 chances when named as an underdog of at least +137 or longer on the moneyline.The moneyline set for this matchup implies the Orioles have a 42.2% chance of coming away with a victory in the contest.Baltimore’s games have gone over the total in 59 of its 137 opportunities.The Orioles have an against the spread record of 64-73-0 in 137 games with a line this season.Kyle Bradish (Orioles probable starter)Bradish (0-1) pitches first for the Orioles to make his second start this season.In his last time out on Tuesday, the right-hander threw six innings against the Boston Red Sox, allowing two earned runs while surrendering four hits.Opposing hitters have compiled a batting average of just .190 against him this season. He has a 3.00 ERA and 15 strikeouts per nine innings over his one game.He meets a Padres offense that ranks 20th in the league with 582 total runs scored while batting .252 as a squad. His opponent has a collective .386 slugging percentage (24th in MLB play) and has hit a total of 119 home runs (29th in the league).Orioles batting statsThe Orioles average 1.2 home runs per game to rank 12th in MLB action with 164 total home runs.So far this year, Baltimore ranks 13th in baseball with a .405 slugging percentage.The Orioles have the 21st-ranked batting average in the league (.242).Baltimore scores the 19th-most runs in baseball (595 total, 4.3 per game).The Orioles rank 23rd in the majors with an on-base percentage of .307.