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Noah Cameron is starting for the Kansas City Royals on Thursday against Zach Neto and the Los Angeles Angels. First pitch is at 7:40 p.m. ET at Kauffman Stadium. The Angels have been listed as +134 moneyline underdogs for this matchup against the favorite Royals (-160). Kansas City is the run-line favorite (-1.5). The total for the game is set at 9 runs.
Check out everything you need from a betting perspective on the Royals-Angels game, regarding the run line, moneyline and total, plus expert picks.
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Angels vs. Royals Highlights | MLB on FOX 
Check out the best moments between the Los Angeles Angels and the Kansas City Royals.
Royals vs. Angels Game Information & OddsWhen: Thursday, September 4, 2025 at 7:40 p.m. ETWhere: Kauffman Stadium in Kansas City, MissouriHow to watch on TV: FDSKC and FDSW Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Royals -160 +134 9 -121 -100 -1.5 +127 -152 Royals vs. Angels PredictionScore Prediction: Royals 4, Angels 3Total Prediction: Under 9 runsWin Probabilities: Royals 55%, Angels 45%Royals vs. Angels Betting InsightsThe Royals have entered the game as favorites 59 times this season and won 34, or 57.6%, of those games.Kansas City has a record of 11-6, a 64.7% win rate, when favored by -160 or more by oddsmakers this season.The moneyline for this contest implies a 61.5% chance of a victory for the Royals.The Angels have won in 48, or 45.7%, of the 105 contests they have been named as odds-on underdogs this year.This year, Los Angeles has won 26 of 53 games when listed as at least +134 or worse on the moneyline.Sportsbooks have implied with the moneyline set for this matchup that the Angels have a 42.7% chance of pulling out a win.Royals Recent Betting PerformanceThe Royals were the moneyline favorite for five of their last 10 games, and went 2-3 in those matchups.Over their last 10 outings (all 10 of them had set totals), the Royals and their opponents combined to hit the over four times.The Royals have put together a 3-7-0 record against the spread over their past 10 games.Royals Recent Stats Stat Avg/Total Record 4-6 Runs Per Game 4.1 HR 10 ERA 4.76 K/9 7.4 Royals Player InsightsThe Royals best hitter thus far this season is Bobby Witt Jr., who’s hitting at a team-leading .297 clip along with 20 homers and 76 RBI.Including all MLB batters, Witt ranks eighth in batting average, 35th in on-base percentage, and 18th in slugging.Maikel Garcia is batting .296 with 34 doubles, five triples, 15 home runs and 52 walks.Garcia is 116th in homers in MLB, and 73rd in RBI.Vinnie Pasquantino leads the Royals in home runs (28) and runs batted in (95).Salvador Perez is batting .239 with 32 doubles, 23 home runs and 23 walks.Angels Recent Betting PerformanceThe Angels have played as underdogs in 10 of their past 10 games and won four of those contests.When it comes to hitting the over, the Angels and their opponents are 4-6-0 in their last 10 games with a total.The Angels have five wins against the spread in their last 10 chances.Angels Recent Stats Stat Avg/Total Record 4-6 Runs Per Game 2.9 HR 12 ERA 5.55 K/9 6.9 Angels Player InsightsTaylor Ward has collected a team-leading 94 runs batted in.Among all batters in the big leagues, Ward ranks 11th in homers and 10th in RBI.Neto has 29 doubles, a triple, 25 home runs and 29 walks while hitting .262.Neto is 36th overall in home runs and 94th in RBI this year.Jo Adell leads the Angels with 32 long balls.Mike Trout is batting .231 with 12 doubles, a triple, 20 home runs and 75 walks.Angels vs. Royals Highlights | MLB on FOX
Check out the best moments between the Los Angeles Angels and the Kansas City Royals.
FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.
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