The Houston Astros (78-67) will visit the Toronto Blue Jays (83-61), in the second game of a three-game series, Wednesday at 7:07 p.m. ET.

The Astros are an underdog (+113 on the moneyline to win) when they take the field at the Blue Jays (-134). The Toronto Blue Jays will hand the ball to Jose Berrios (9-5, 4.02 ERA), who is looking for win No. 10 on the season, and the Astros will turn to Jason Alexander (4-1, 4.68 ERA).

These squads meet again following the Blue Jays’ 4-3 victory over the Astros yesterday. Jeff Hoffman (1.0 IP, 0 R, 0 H, 0 K) picked up the win for the Blue Jays. George Springer went 1 for 5 with a home run and an RBI to lead the team on offense. Craig Kimbrel (0.1 IP, 0 R, 1 H, 1 K) was credited with the loss on the mound for the Astros.

Ahead of the Blue Jays vs. Astros matchup, here’s everything you need to get ready for Wednesday’s baseball action, including viewing options.

Toronto Blue Jays vs. Houston Astros odds, line and spread

MLB odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 3:16 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Favorite: Blue Jays (-134, bet $134 to win $100)Underdog: Astros (+113, bet $100 to win $113)Over/under: 9Blue Jays vs. Astros: Game time and live stream infoGame day: Wednesday, September 10, 2025Game time: 7:07 p.m. ETLocation: Toronto, OntarioStadium: Rogers CentreTV channel: SNET and SCHNLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)

Watch Blue Jays vs. Astros on Fubo!

Blue Jays stats and trendsBlue Jays betting recordsThe Blue Jays have been favorites in 70 games this season and won 41 (58.6%) of those contests.Toronto has a record of 32-14 in games when bookmakers favor them by at least -134 on the moneyline.The sportsbooks’ moneyline implies a 57.3% chance of a victory for the Blue Jays.Games involving Toronto have gone over the total set by bookmakers in 78 of 143 chances this season.The Blue Jays are 83-60-0 against the spread this season.José Berrios (Blue Jays probable starter)Berrios (9-5 with a 4.02 ERA and 131 strikeouts in 154 2/3 innings pitched) looks for his 10th win when he gets the start for the Blue Jays, his 29th of the season.The right-hander’s most recent time out was on Tuesday, Sept. 2 against the Cincinnati Reds, when he tossed two innings, surrendering two earned runs while allowing five hits.The 31-year-old has an ERA of 4.02, with 7.6 strikeouts per nine innings, in 28 games this season. Opposing hitters have a .253 batting average against him.Berrios is trying to collect his 15th quality start of the year in this matchup.Berrios will try to collect his 23rd matchup of five or more innings pitched this season. He’s averaging 5.5 innings per appearance.He has had six appearances this season in which he kept his opponents to zero earned runs.The opposing Astros offense has a collective .253 batting average, and is sixth in the league with 1245 total hits and 25th in MLB action with 612 runs scored. It has the 15th-ranked slugging percentage (.401) and ranks 18th in home runs (160) in all of MLB.The 31-year-old ranks 32nd in ERA (4.02), 35th in WHIP (1.293), and 39th in K/9 (7.6) among qualifying pitchers in MLB action this season.Blue Jays batting statsThe Blue Jays have hit 175 homers this season, which ranks 11th in the league.Hitters for Toronto have a combined .432 slugging percentage this season, which ranks fifth in MLB.The Blue Jays lead baseball with a .269 batting average.Toronto is among the highest-scoring teams in the majors, ranking fifth with 719 total runs this season.The Blue Jays get on base at a .338 clip, best in the league.Toronto has the fewest strikeouts in MLB, whiffing only 6.8 times per game on average.Astros stats and trendsAstros betting recordsThe Astros have been victorious in 28, or 56%, of the 50 contests they have been chosen as underdogs in this season.This year, Houston has won 15 of 25 games when listed as at least +113 or worse on the moneyline.The Astros have an implied victory probability of 46.9% according to the moneyline set for this matchup.Contests with Houston has gone over the total set by bookmakers in 65 of 145 chances this season.In 145 games with a line this season, the Astros have a mark of 72-73-0 against the spread.Jason Alexander (Astros probable starter)Alexander gets the start for the Astros, his 10th of the season. He is 4-1 with a 4.68 ERA and 52 strikeouts over 59 2/3 innings pitched.In his last appearance on Thursday, the right-hander went five innings against the New York Yankees, allowing three earned runs while surrendering six hits.The 32-year-old has put up an ERA of 4.68, with 7.8 strikeouts per nine innings in 14 games this season. Opponents are hitting .258 against him.Alexander has registered four quality starts this season.Alexander is seeking his seventh straight outing lasting five or more innings. He averages 4.2 innings per start.In five of his appearances this season he did not allow an earned run.He meets a Blue Jays offense that ranks fifth in the league with 719 total runs scored while batting .269 as a unit. His opponent has a collective .432 slugging percentage (fifth in MLB action) and has hit a total of 175 home runs (11th in the league).Astros batting statsThe Astros rank 18th in baseball with 160 total home runs.So far this season, Houston ranks 15th in the majors, slugging .401.The Astros have the sixth-best batting average in the league (.253).The offense for Houston is the No. 25 offense in the majors, scoring 4.2 runs per game (612 total runs).The Astros’ .318 on-base percentage is 14th in MLB.

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