On Saturday, the St. Louis Cardinals (72-75) are visiting the Milwaukee Brewers (89-58), at 8:15 p.m. ET. The Cardinals have lost three straight, and the Brewers have dropped three in a row.
The Cardinals are an underdog (+139 moneyline odds to win) when they visit the Brewers (-167). The matchup on the mound for this contest is set with the Milwaukee Brewers looking to Jacob Misiorowski (5-2), and Sonny Gray (13-8) getting the nod for the St. Louis Cardinals.
The Brewers lost 6-3 against the Rangers Wednesday, with Freddy Peralta taking the loss. He threw five innings, giving up five earned runs on six hits while striking out nine. Brice Turang went 2 for 5 with a home run and an RBI to lead the Brewers offensively.
The Cardinals fell to the Mariners 4-2 Wednesday. Thomas Saggese went 4 for 5 with a double and an RBI in the defeat, while Ryan Fernandez took the loss on the mound, pitching one inning, giving up one earned run on one hit while striking out one.
Ahead of this Brewers vs. Cardinals showdown, here’s what you need to get ready for Saturday’s MLB action, including viewing options.
Milwaukee Brewers vs. St. Louis Cardinals odds, line and spread
MLB odds courtesy of BetMGM Sportsbook. Odds updated Friday at 9:16 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Favorite: Brewers (-167, bet $167 to win $100)Underdog: Cardinals (+139, bet $100 to win $139)Over/under: 7.5Brewers vs. Cardinals: Game time and live stream infoGame day: Saturday, September 13, 2025Game time: 8:15 p.m. ETLocation: Milwaukee, WisconsinStadium: American Family FieldTV channel: FOXLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Watch Brewers vs. Cardinals on Fubo!
Brewers stats and trendsBrewers betting recordsThe Brewers have been favorites in 83 games this season and won 53 (63.9%) of those contests.Milwaukee has a record of 14-3 in games when sportsbooks favor them by at least -167 on the moneyline.The moneyline for this contest implies a 62.5% chance of a victory for the Brewers.Milwaukee’s games have gone over the total in 70 of its 147 chances.The Brewers have an ATS record of 83-64-0 in 147 games with a spread this season.Jacob Misiorowski (Brewers probable starter)The Brewers will send Misiorowski (5-2) out to make his 13th start of the season. He is 5-2 with a 4.09 ERA and 77 strikeouts through 55 2/3 innings pitched.His last time out was on Sunday against the Pittsburgh Pirates, when the righty went seven innings, surrendering one earned run while giving up three hits.In 12 games this season, the 23-year-old has an ERA of 4.09, with 12.6 strikeouts per nine innings. Opponents are batting .185 against him.Misiorowski has three quality starts this year.Misiorowski has pitched five or more innings in a game six times this year entering this game.He has had three appearances this season in which he held his opponents to zero earned runs.He will match up with a Cardinals offense that ranks 18th in MLB with 1206 total hits (on a .244 batting average). The squad also slugs a collective .379 (27th in MLB) with 138 total home runs (28th in MLB).Head-to-head against the Cardinals this season, Misiorowski has thrown five innings without giving up a hit or an earned run while striking out five.Brewers batting statsThe Brewers rank 20th in Major League Baseball with 157 home runs.Hitters for Milwaukee have combined for a team rank of 12th in the majors with a .408 team slugging percentage.The Brewers have a team batting average of .260 this season, which ranks second among MLB teams.Milwaukee has scored the second-most runs in the majors this season with 743.The Brewers have an OBP of .333 this season, which ranks second in MLB.Milwaukee is one of the most-disciplined teams at the plate this season, ranking fifth with an average of 7.8 strikeouts per game.Cardinals stats and trendsCardinals betting recordsThe Cardinals have won in 38, or 47.5%, of the 80 contests they have been named as odds-on underdogs this year.St. Louis has a mark of 7-13 in contests where oddsmakers favor it by +139 or worse on the moneyline.The moneyline set for this matchup implies the Cardinals have a 41.8% chance of walking away with the win.Contests with St. Louis has gone over the total set by bookmakers in 73 of 146 chances this season.The Cardinals have posted a record of 73-73-0 against the spread this season.Sonny Gray (Cardinals probable starter)Gray (13-8 with a 4.45 ERA and 179 strikeouts in 163 2/3 innings pitched) gets the start for the Cardinals, his 30th of the season.The righty’s last time out was on Sunday against the San Francisco Giants, when he tossed 5 1/3 innings, surrendering three earned runs while allowing two hits.In 29 games this season, the 35-year-old has an ERA of 4.45, with 9.8 strikeouts per nine innings. Opponents are hitting .259 against him.Gray enters this matchup with 12 quality starts under his belt this year.Gray will look to go five or more innings for his 10th straight start. He’s averaging 5.6 frames per outing.He has had six appearances this season in which he did not allow an earned run.He will take the hill against a Brewers offense that ranks third in the league with 1300 total hits (on a .260 batting average). The squad also slugs a collective .408 (12th in the league) with 157 total home runs (20th in MLB play).In 10 1/3 innings over two appearances against the Brewers this season, Gray has a 7.84 ERA and a 1.839 WHIP while his opponents are batting .349.The 35-year-old’s 4.45 ERA ranks 41st, 1.222 WHIP ranks 26th, and 9.8 K/9 ranks 13th among qualifying pitchers this season.Cardinals batting statsThe Cardinals have hit the third-fewest home runs in MLB play this season (138).This season, St. Louis is slugging .379, the fourth-lowest percentage in baseball.The Cardinals are 18th in the majors with a .244 batting average.Averaging 4.3 runs per game (629 total), St. Louis is the 21st-highest scoring team in baseball.The Cardinals’ .313 on-base percentage ranks 19th in the majors.