At PETCO Park on Monday, the Milwaukee Brewers (95-60) begin a three-game series against the San Diego Padres (84-71), at 9:40 p.m. ET.
The favored Padres (-130 on the moneyline to win) host the Brewers (+110). The San Diego Padres will give the start to Nick Pivetta (13-5, 2.81 ERA), who is looking for win No. 14 on the season, and the Brewers will counter with Brandon Woodruff (7-2, 3.20 ERA).
The Padres won their most recent game against the White Sox on Saturday by a 7-3 score. Jackson Merrill went 2 for 4 with a double, a home run and an RBI to lead them offensively. Adrian Morejon picked up the win on the strength of 1 1/3 innings without giving up an earned run on one hit.
The Brewers beat the Cardinals 3-2 Saturday. Andrew Vaughn led the way offensively after going 1 for 1 with a double and an RBI, and Jared Koenig got the win, pitching two innings without giving up a hit or an earned run while striking out one.
Ahead of the Padres vs. Brewers matchup, here’s what you need to get ready for Monday’s baseball action, including viewing options.
San Diego Padres vs. Milwaukee Brewers odds, line and spread
MLB odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 3:21 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Favorite: Padres (-130, bet $130 to win $100)Underdog: Brewers (+110, bet $100 to win $110)Over/under: 7Padres vs. Brewers: Game time and live stream infoGame day: Monday, September 22, 2025Game time: 9:40 p.m. ETLocation: San Diego, CaliforniaStadium: PETCO ParkTV channel: SDPA and FDSWILive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Watch Padres vs. Brewers on Fubo!
Padres stats and trendsPadres betting recordsThis season, the Padres have won 51 out of the 87 games, or 58.6%, in which they’ve been favored.San Diego has a record of 44-29 in games when oddsmakers favor them by at least -130 on the moneyline.The implied probability of a win from the Padres, based on the moneyline, is 56.5%.Games involving San Diego have gone over the total set by bookmakers in 66 of 155 chances this season.The Padres are 83-72-0 against the spread this season.Nick Pivetta (Padres probable starter)Pivetta (13-5 with a 2.81 ERA and 185 strikeouts in 176 2/3 innings pitched) gets the start for the Padres, his 31st of the season.The righty last appeared on Wednesday against the New York Mets, when he threw 4 2/3 innings, allowing three earned runs while giving up seven hits.In 30 games this season, the 32-year-old has amassed an ERA of 2.81, with 9.5 strikeouts per nine innings. Opponents are hitting .195 against him.Pivetta is looking to pick up his 20th quality start of the year in this outing.Pivetta heads into the matchup with 25 outings of five or more innings pitched this year.He has held his opponents without an earned run in seven of his 30 outings this season.He will take the hill against a Brewers squad that is batting .261 as a unit (second in MLB). It is also slugging a collective .409 (12th in MLB) with 163 total home runs (20th in MLB).Among qualifying pitchers in MLB action this season, the 32-year-old’s 2.81 ERA ranks eighth, .966 WHIP ranks fifth, and 9.5 K/9 ranks 15th.Padres batting statsThe Padres have hit just 141 homers this season, which ranks 29th in the league.Hitters for San Diego have combined for a team rank of 23rd in the majors with a .388 team slugging percentage.The Padres’ .252 batting average is among the best in baseball, ranking seventh in MLB.San Diego has scored 662 runs (4.3 per game) this season, which ranks 18th in MLB.The Padres are among the best in the league at getting on base, ranking ninth with an OBP of .321.San Diego is one of the most-disciplined teams at the plate this season, ranking third with an average of 7.1 strikeouts per game.Brewers stats and trendsBrewers betting recordsThe Brewers have been underdogs in 63 games this season and have come away with the win 35 times (55.6%) in those contests.This season, Milwaukee has been victorious 20 times in 39 chances when named as an underdog of at least +110 or longer on the moneyline.Bookmakers have implied with the moneyline set for this matchup that the Brewers have a 47.6% chance of pulling out a win.Milwaukee and its opponents have hit the over in 75 of its 155 games with a total set by oddsmakers this season.In 155 games with a line this season, the Brewers have a mark of 87-68-0 against the spread.Brandon Woodruff (Brewers probable starter)Woodruff (7-2 with a 3.20 ERA and 83 strikeouts in 64 2/3 innings pitched) gets the start for the Brewers, his 13th of the season.In his most recent time out on Wednesday, the righty went five innings against the Los Angeles Angels, giving up one earned run while surrendering two hits.The 32-year-old has put up an ERA of 3.20, with 11.6 strikeouts per nine innings in 12 games this season. Opponents have a .188 batting average against him.Woodruff has recorded six quality starts this season.Woodruff will aim to pitch five or more innings for his third straight start. He’s averaging 5.4 frames per outing.He has had three appearances this season that he held his opponents to zero earned runs.He will face a Padres offense that ranks 18th in the league with 662 total runs scored while batting .252 as a squad. His opponent has a collective .388 slugging percentage (23rd in MLB action) and has hit a total of 141 home runs (29th in the league).Brewers batting statsThe Brewers rank 20th in baseball with 163 home runs. They average 1.1 per game.So far this year, Milwaukee’s .409 slugging percentage ranks 12th in the majors.The Brewers have the second-best batting average in the league (.261).The offense for Milwaukee is No. 3 in MLB, scoring 5.1 runs per game (789 total runs).The Brewers have a league-best .334 on-base percentage.