The Milwaukee Brewers (95-62) visit the San Diego Padres (86-71) Tuesday for the second game of a 3-game series at Petco Park in San Diego, California. First pitch is scheduled for 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Brewers vs. Padres odds and make our expert MLB picks and predictions for the best bets.
Season series: Padres lead 3-1
Milwaukee has dropped back-to-back games after falling 5-4 in 11 innings Monday at San Diego as a -104 pick’em. DH Christian Yelich drove in 2 runs for the Brewers, who clinched the NL Central Saturday.
C Freddy Fermin hit a walk-off RBI single in the 11th inning, securing San Diego’s third straight win and its fourth playoff berth in 6 years. The Padres are still attempting to overtake the division-leading LA Dodgers, whose magic number is 3 to win the NL West.
Play our free daily Pick’em Challenge and win! Play now!
Brewers at Padres projected starters
LHP Bruce Zimmermann vs. RHP Randy Vasquez
Zimmermann (2-0, 4.73 ERA in 2023) makes his season debut. He allowed 17 hits and no walks while striking out 14 in 13 1/3 innings over 7 relief appearances in 2023 with the Baltimore Orioles.
Making his first MLB appearance since 2023 and first start since 20222025 stats with Triple-A Nashville: 10-7, 4.11 ERA (138 IP, 63 ER), 1.23 WHIP, 7.1 K/9 in 21 starts and 7 relief appearancesCareer road stats: 2-7, 6.66 ERA (75 2/3 IP, 56 ER), 1.60 WHIP, 7.3 K/9 in 14 starts and 4 relief appearancesHas never faced Padres
Vasquez (5-7, 3.94 ERA) makes his 26th start. He has a 1.36 WHIP, 3.6 BB/9 and 5.3 K/9 through 125 2/3 innings.
Last start: Loss, 2 1/3 IP, 4 ER, 4 H, 1 BB, 3 K in 6-1 defeat at New York Mets ThursdayCareer vs. Brewers: 1-0, 0.00 ERA (9 2/3 IP), 1.45 WHIP, 7 H, 7 BB, 5 K in 2 startsBrewers at Padres odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:13 p.m. ET.
Moneyline (ML): Brewers -105 (bet $105 to win $100) | Padres -115 (bet $115 to win $100)Run line (RL)/Against the spread (ATS): Brewers -1.5 (+155) | Padres +1.5 (-190)Over/Under (O/U): 8.5 (O: -115 | U: -105)
Slide into: BaseballHQ.com for your fantasy baseball news. For decades, BHQ has been helping players just like you win! BHQ offers full-season subscriptions. Sign up today!
Brewers at Padres picks and predictionsPrediction
Padres 6, Brewers 4
BET PADRES (-115).
The Padres are still fighting to win their division and have won each of their last 3 games. They’re facing Zimmermann, who has not seen big-league action since 2023. While the Brewers are trying to maintain momentum with the playoffs rapidly approaching, they have already secured the top spot in their division and hold a 2½-game lead over the Philadelphia Phillies for MLB’s best record. In 2 previous starts, Vasquez has found a lot of success against the Brewers.
PASS.
In a matchup between 2 of MLB’s top teams, the moneyline is the best play.
BET OVER 8.5 (-115).
The Brewers have scored at least 4 runs in 6 of their last 10 games, going 6-4 to the Over, while allowing 5 or more in 3 of their last 4.
The Padres have scored 4 or more runs in 2 of their last 3 games and in 5 of their last 9. They have allowed 4 or more runs in 6 of their last 8 and have hit the Over in 6 of their last 9.
For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.
Follow SportsbookWire on Twitter/X and like us on Facebook.