On Friday, a series opener is on the schedule, with the Washington Nationals (65-94) hosting the Chicago White Sox (58-100) at 6:45 p.m. ET.
The Nationals are favored (-130 moneyline odds) when they host the White Sox (+110). The matchup on the mound for this contest is set with the Washington Nationals looking to Cade Cavalli (3-1), and Yoendrys Gomez (3-3) getting the nod for the Chicago White Sox.
The Nationals knocked off the Braves by a 4-3 score in their most recent game Wednesday. James Wood went 2 for 4 with two home runs and two RBIs to lead them offensively while Mitchell Parker got the win after throwing 2/3 of an inning without giving up a hit or an earned run.
The White Sox were defeated by the Yankees 8-1 Wednesday. Miguel Vargas went 1 for 3, and Jonathan Cannon was handed the loss, throwing 4 1/3 innings, giving up five earned runs on six hits while striking out six.
Get ready for the Nationals vs. White Sox with everything you need to know before Friday’s baseball action, including viewing options.
Washington Nationals vs. Chicago White Sox odds, line and spread
MLB odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 9:16 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Favorite: Nationals (-130, bet $130 to win $100)Underdog: White Sox (+110, bet $100 to win $110)Over/under: 9Nationals vs. White Sox: Game time and live stream infoGame day: Friday, September 26, 2025Game time: 6:45 p.m. ETLocation: Washington D.C.Stadium: Nationals ParkTV channel: MASN2 and CHSNLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Watch Nationals vs. White Sox on Fubo!
Nationals stats and trendsNationals betting recordsThis season, the Nationals have won six out of the 18 games, or 33.3%, in which they’ve been favored.Washington has a record of 2-8 in games when sportsbooks favor them by at least -130 on the moneyline.The Nationals have a 56.5% chance to win this game based on the implied probability of the moneyline.Washington and its opponents have hit the over in 78 of its 158 games with a total this season.The Nationals are 78-80-0 against the spread this season.Cade Cavalli (Nationals probable starter)The Nationals will send Cavalli (3-1) out for his 10th start of the season. He is 3-1 with a 4.23 ERA and 34 strikeouts through 44 2/3 innings pitched.In his last appearance on Saturday, the right-hander threw five scoreless innings against the New York Mets while surrendering five hits.The 27-year-old has an ERA of 4.23, with 6.9 strikeouts per nine innings, in nine games this season. Opponents are batting .282 against him.Cavalli has two quality starts under his belt this season.Cavalli will try to build on a five-game streak of going five or more innings (he’s averaging 4.9 innings per outing).He has made three appearances this season in which he did not give up an earned run.He will face a White Sox team that is batting .232 as a unit (27th in MLB). It is also slugging a collective .371 (29th in MLB) with 157 total home runs (23rd in MLB).Nationals batting statsThe Nationals have hit just 152 homers this season, which ranks 27th in the league.Hitters for Washington have combined for a team rank of 23rd in the majors with a .387 team slugging percentage.The Nationals rank 21st in MLB with a .242 team batting average.Washington has scored 672 runs (4.2 per game) this season, which ranks 20th in MLB.The Nationals have an on-base percentage of .305 this season, which ranks 23rd in the league.Washington ranks 13th in MLB in strikeouts per game with an average of 8.3 whiffs per contest.White Sox stats and trendsWhite Sox betting recordsThe White Sox have come away with 57 wins in the 155 contests they have been listed as the underdogs in this season.This year, Chicago has won 51 of 139 games when listed as at least +110 or worse on the moneyline.The White Sox have an implied victory probability of 47.6% according to the moneyline set by oddsmakers for this matchup.Chicago and its opponents have gone over in 71 of its 158 games with a total set by sportsbooks this season.The White Sox have posted a record of 92-66-0 against the spread this season.Yoendrys Gomez (White Sox probable starter)Gomez gets the start for the White Sox, his ninth of the season. He is 3-3 with a 4.92 ERA and 53 strikeouts over 56 2/3 innings pitched.The right-hander last pitched on Saturday against the San Diego Padres, when he went 5 1/3 innings, allowing three earned runs while giving up six hits.In 20 games this season, the 25-year-old has amassed a 4.92 ERA and 8.4 strikeouts per nine innings, while giving up a batting average of .239 to opposing batters.Gomez has yet to record a quality start so far this year.Gomez is looking for his fifth straight appearance lasting five or more innings. He averages 2.8 innings per start.He has made seven appearances this season in which he did not give up an earned run.He will face a Nationals team that is hitting .242 as a unit (21st in the MLB). They are also slugging a collective .387 (23rd in the league) with 152 total home runs (27th in MLB play).White Sox batting statsThe White Sox average 1.0 home run per game to rank 23rd in MLB play with 157 total home runs.So far this year, Chicago’s .371 slugging percentage is the second-lowest percentage in the majors.The White Sox are 27th in the majors with a .232 batting average.Chicago is the third-lowest scoring team in MLB play averaging 3.9 runs per game (621 total).The White Sox are 27th in the majors with a .301 on-base percentage.