In the final game of a three-game set at Angel Stadium, the Houston Astros (86-75) take on the Los Angeles Angels (72-89), Sunday at 3:07 p.m. ET.
As the favorite, the Astros (-143 on the moneyline) visit the Angels (+121). The Astros will give the ball to Lance McCullers (2-5) versus the Angels and Samuel Aldegheri (0-1).
These clubs meet again following the Astros’ 6-1 victory over the Angels yesterday. J.P. France (3.0 IP, 1 R, 2 H, 5 K) picked up the win for the Astros. Christian Walker went 2 for 4 with two home runs and two RBIs to lead the team on offense. Caden Dana (7.0 IP, 5 R, 5 H, 5 K) was credited with the loss on the mound for the Angels.
Ahead of the Astros vs. Angels matchup, here is what you need to prepare for Sunday’s baseball action, including viewing options.
Houston Astros vs. Los Angeles Angels odds, line and spread
MLB odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 3:17 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Favorite: Astros (-143, bet $143 to win $100)Underdog: Angels (+121, bet $100 to win $121)Over/under: 9Astros vs. Angels: Game time and live stream infoGame day: Sunday, September 28, 2025Game time: 3:07 p.m. ETLocation: Anaheim, CaliforniaStadium: Angel StadiumTV channel: FDSW and SCHNLive stream: Watch LIVE with Fubo! (Regional restrictions may apply)
Watch Astros vs. Angels on Fubo!
Astros stats and trendsAstros betting recordsThe Astros have been favorites in 104 games this season and won 54 (51.9%) of those contests.Houston has entered 42 games this season favored by -143 or more and is 23-19 in those contests.The Astros have a 58.8% chance to win this game based on the implied probability of the moneyline.Houston and its opponents have hit the over in 72 of its 161 games with a total this season.In 161 games with a spread this season, the Astros are 80-81-0 ATS.Lance McCullers (Astros probable starter)McCullers (2-5) gets the starting nod for the Astros in his 13th start of the season. He has a 6.88 ERA in 52 1/3 innings pitched, with 57 strikeouts.His last appearance came out of the bullpen on Thursday, Sept. 11 when the right-hander tossed two innings against the Toronto Blue Jays, surrendering one earned run while allowing two hits.The 31-year-old has amassed an ERA of 6.88, with 9.8 strikeouts per nine innings, in 15 games this season. Opposing hitters have a .276 batting average against him.McCullers is looking to collect his fourth quality start of the season in this outing.McCullers heads into this game with four outings of five or more innings pitched this year.He has made four appearances this season in which he did not allow an earned run.He will match up with an Angels offense that ranks 29th in MLB with 1203 total hits (on a .225 batting average). The team also slugs a collective .398 (15th in MLB) with 225 total home runs (fourth in MLB).McCullers has a 9.00 ERA and a 2.500 WHIP against the Angels this season in two innings pitched, allowing a .333 batting average over one appearance.Astros batting statsThe Astros’ 178 home runs rank 17th in Major League Baseball.Fueled by 436 extra-base hits, Houston ranks 17th in MLB with a .397 slugging percentage this season.The Astros’ .250 batting average ranks 11th in the league this season.Houston has scored 680 runs (4.2 per game) this season, which ranks 21st in MLB.The Astros have an OBP of .315 this season, which ranks 15th in MLB.Houston is one of the most-disciplined teams at the plate this season, ranking seventh with an average of 8.0 strikeouts per game.Angels stats and trendsAngels betting recordsThe Angels have been victorious in 53, or 43.4%, of the 122 contests they have been chosen as underdogs in this season.Los Angeles has a win-loss record of 33-44 when favored by +121 or worse by oddsmakers this year.The moneyline set for this matchup implies the Angels have a 45.2% chance of coming away with a victory in the contest.Los Angeles and its opponents have gone over in 85 of its 161 games with a total set by sportsbooks this season.The Angels have an against the spread record of 84-77-0 in 161 games with a line this season.Samuel Aldegheri (Angels probable starter)Aldegheri (0-1) gets the start for the Angels, his second of the season.In his last appearance on Wednesday, the left-hander tossed 4 2/3 innings against the Kansas City Royals, allowing three earned runs while surrendering seven hits.In three games this season, he has an 8.00 ERA and 7.0 strikeouts per nine innings while opponents are batting .342 against him.He will face an Astros offense that ranks 21st in the league with 680 total runs scored while batting .250 as a squad. His opponent has a collective .397 slugging percentage (17th in MLB action) and has hit a total of 178 home runs (17th in the league).Angels batting statsThe Angels average 1.4 home runs per game to rank fourth in MLB play with 225 total home runs.So far this year, Los Angeles is 15th in the majors with a .398 slugging percentage.The Angels have the second-worst batting average in the majors (.225).The offense for Los Angeles is the No. 25 offense in MLB, scoring 4.2 runs per game (671 total runs).The Angels rank 28th in baseball with a .298 on-base percentage.