The Cleveland Guardians are back in the postseason for the seventh time in the past 10 seasons — and for the second time in as many years under manager Stephen Vogt.

The Guardians are still looking for their first World Series title since 1948, which, of course, is the longest drought in pro sports. Cleveland reached the ALCS a season ago before falling to the New York Yankees in five games.

Cleveland enters the postseason red hot, since they went 24-8 in their past 32 games to overtake the Detroit Tigers for the American League Central crown.

Here’s a look at the Guardians’ World Series odds and best playoff bets to make for October.

Cleveland Guardians World Series odds and moreGuardians to win World Series: (+3000 at DraftKings)Guardians to win American League: (+1100 at DraftKings)Guardians to win AL Wild Card Series vs Tigers: (-104 at FanDuel)

The Guardians have been on a tear and will enter as one of three AL division champions, but they have the longest odds to come out of the American League.

Cleveland is a slight underdog in its best-of-three AL Wild Card Series against the Detroit Tigers, based mainly on likely AL Cy Young Award winner Tarik Skubal pitching Game 1 for the Tigers.

But to win the AL pennant, the Guardians will need to win an extra postseason series over either the Seattle Mariners or Toronto Blue Jays, each of whom received a bye to the ALDS.

The Texas Rangers are the only American League club to go from the Wild Card series to the World Series in the three seasons of the best-of-three format, though it happened twice in the NL in three years.

The Guardians, who will play the Wild Card series at home, may knock off Skubal and the reeling Tigers like they did in five games in the 2024 ALDS.

Cleveland’s road is arduous. The Guardians would have to win nine games over three AL playoff series — all against top-notch teams. The Guardians seem likely to run out of gas at some point.

Best Guardians postseason prop betsTeam to progress further — Guardians vs. Reds: Guardians (+140 at DraftKings)Steven Kwan postseason batting average Over .256: (-110 at DraftKings)AL Wild Card Game 1/Series double: G1 Cleveland/Series Cleveland (+185 at FanDuel)Team to progress further: Guardians vs Reds, Guardians

Best odds: +140 at DraftKings

DraftKings offers a slew of postseason special props, and in this one, the battle of Ohio is on display.

The Reds snuck in as the majors’ last postseason team, but their reward is a matchup against the reigning World Series champion Los Angeles Dodgers in a best-of-3 set at Dodger Stadium. The Reds went 83-79, the second-fewest wins of any playoff team in MLB history over a 162-game season.

Cincinnati was 1-5 against the Dodgers during the regular season and was outscored 30-15 in those six games. They also just got swept at Chavez Ravine a month ago.

So the Guardians at least match up well against the Tigers. The Reds are likely to get bounced swiftly by the LA. This is a three-way betting market, so you will lose if you pick Cleveland and both teams are eliminated at the same stage, but the Guardians are way more likely to advance than the Reds. The odds for both teams to be eliminated in the same round are +135.

DraftKings has Cincinnati as a +205 underdog to reach the NLDS.

Steven Kwan postseason batting average: Over .256

Best odds: -110 at DraftKings

When I saw this number, I was surprised at how low it was. Kwan, the table-setting outfielder who is nearly impossible to strike out, boasts a .347 career postseason batting average in 80 plate appearances, including his 8 for 16 (.500) performance in the ALDS vs the Tigers last year.

Maybe the Guardians won’t have the same offense as they did last year in the postseason, but Kwan hit .272 in the regular season and hit .279 in September while helping the Guardians get into the playoffs.

AL Wild Card Game 1/Series double: G1 Cleveland/Series Cleveland

Best odds: +185 at FanDuel

The Guardians are a healthy underdog in Game 1 against Skubal, but they won twice in starts Skubal made against them in 2025. Of course, Cleveland beat the 2024 AL Cy Young winner in Game 5 of the ALDS a season ago.

The winner of Game 1 will be in the proverbial catbird seat, especially if it is Cleveland that wins Tuesday. This wager accounts for the potential of the Guardians to lose Game 2 and win the series, rather than wagering the exacta of Cleveland to win 2-0, with still-great plus-money odds.

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