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The Los Angeles Dodgers welcome a postseason team from last season, the Cleveland Guardians, to Chavez Ravine for a three-game set.

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Game 1 sees Roki Sasaki make his first start since last May, while Cleveland counters with prospect Parker Messick.

That’s part of why my Guardians vs. Dodgers predictions and MLB picks expect the Over to hit in this interleague matchup, with first pitch at Dodger Stadium scheduled for 10:10 pm ET on Monday, March 30.

Guardians vs Dodgers predictionsGuardians vs Dodgers best bet: Over 8.5 (-120)

The Los Angeles Dodgers lineup is even more ridiculous with Kyle Tucker in the middle of it, as they scored 16 runs over the weekend. 

They face Parker Messick, a lefty making just his seventh career start. Messick isn’t a hard thrower, and if he misses his spots against this Dodgers lineup, he could be in trouble.

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Meanwhile, the Cleveland Guardians look like they finally might have another bat to support Jose Ramirez in Chase DeLauter, who’s already hit four dingers.

It’s hard to know what L.A. will get out of Roki Sasaki as a starter, so expect some runs.

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COVERS INTEL:

The Dodgers ranked third in OPS and fourth in wRC+ when facing left-handed pitching last season.

Guardians vs Dodgers same-game parlay (SGP)

Tucker is off to a solid if unspectacular start with his new team. He’s 2-for-11 with two RBI and three runs scored.

I like this matchup for him tonight. He’s a lefty who always hits southpaws as well as he does right-handers, so we’re almost always getting value when he’s got a lefty-lefty matchup.

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On the other side, no one’s had a hotter start to the season than Chase DeLauter. The rookie phenom has already slugged four home runs with a 1.412 OPS.

Guardians vs Dodgers SGP

Chase DeLauter Over 0.5 RBI

Guardians vs Dodgers home run pick: Mookie Betts (+440)

Mookie Betts is my favorite value to go yard at Chavez Ravine tonight at this price. Betts had a terrible, slow start to last season and ended up with just 20 home runs. Still, seven of those came against left-handers in nearly 300 fewer at-bats.

Betts had a .750 OPS vs. lefties last season and has a career .897 OPS against them. He’s also gone deep once already this season, so I’m betting another early-season slump is unlikely.

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2026 Transparency record

Best bets: 1-1, +0.31 units

Guardians vs Dodgers odds

Moneyline: Cleveland +154 | Los Angeles -184

Run line: Cleveland +1.5 (-132) | Los Angeles -1.5 (+110)

Over/Under: Over 8.5 | Under 8.5

Guardians vs Dodgers trend

The Dodgers have hit the team total Over in 22 of their last 35 games, good for +8.80 Units and a 22% ROI. Find more MLB betting trends for Guardians vs. Dodgers.

How to watch Guardians vs Dodgers and game info

Location

Dodger Stadium, Los Angeles, CA

Date

Monday, March 30, 2026

First pitch

10:10 p.m. ET

TV

CLEG, SportsNet LA

Guardians starting pitcher

Parker Messick
(2025: 3-1, 2.72 ERA)

Dodgers starting pitcher

Roki Sasaki
(2025: 1-1, 4.46 ERA)

Guardians vs Dodgers latest injuriesGuardians vs Dodgers weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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