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The Los Angeles Angels hope to snap a three-game losing streak when they face the Chicago Cubs tonight at Wrigley Field.

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The forecast promises a cold, miserable night, and my Angels vs. Cubs predictions expect LA starter Jose Soriano and his sinker-slider combo to rack up the strikeouts.

Read on for my MLB picks for Tuesday, March 31.

Angels vs Cubs predictionsAngels vs Cubs best bet: Jose Soriano Over 4.5 strikeouts (-108)

Jose Soriano is riding a jaw-dropping 41.3% whiff rate from his 2026 opener, where he struck out seven Astros in six innings of work.

This follows a strong spring where the Los Angeles Angels righty struck out 13 across 11 2/3 and eight punchouts per nine frames in 2025.

The Chicago Cubs lineup presents multiple strikeout candidates, and they’ve struck out in 22% of their 91 plate appearances against right-handed arms in 2026.

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Cold, heavy air at Wrigley Field plays right into Soriano’s hard sinker and devastating slider combo. Back him to punch out at least five tonight.

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COVERS INTEL:

Soriano averaged 3.7 pitches per batter and struck out 8.05 batters per nine in 2025, and seven Astros on Opening Day at Houston.

Angels vs Cubs same-game parlay (SGP)

Cold weather, limited scoring, and the more reliable arm on the mound sum up this three-leg same-game parlay.

Soriano was excellent on the road last season (8-3), and he just threw six scoreless innings in Houston. His 69.2% ground-ball rate limits damage and keeps traffic off the bases.

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Jameson Taillon allowed 26 earned runs across 13 1/3 spring innings, and he’s hard to trust right now. In a game where runs will be scarce, that edge on the mound leans toward the Halos.

Angels vs Cubs SGP

Jose Soriano Over 4.5 strikeouts

Angels vs Cubs home run pick: Mike Trout (+310)

Mike Trout doesn’t need much of an invitation, and Taillon is practically rolling out the red carpet.

Ten home runs and nine walks in just over 13 spring innings tell you that he is a pitcher who can’t find the zone and is getting destroyed when he does.

Trout has already taken Taillon deep, and the Angels slugger launched two bombs on Opening Day at Houston. I’ll back him to crack one tonight.

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2026 Transparency record

Best bets: 1-1, -0.2 units

Angels vs Cubs odds

Moneyline: Los Angeles +120 | Chicago -142

Run line: Los Angeles +1.5 (-188) | Chicago -1.5 (+155)

Over/Under: Over 7.5 (+116) | Under 7.5 (-142)

Angels vs Cubs trend

The Chicago Cubs have hit the Game Total Under in 64 of their last 117 games (+13.65 Units / 11% ROI). Find more MLB betting trends for Angels vs. Cubs.

How to watch Angels vs Cubs and game info

Location

Wrigley Field, Chicago, IL

Date

Tuesday, March 31, 2026

First pitch

7:40 p.m. ET

TV

FDSN West, Marquee

Angels starting pitcher

Jose Soriano
(1-0, 0.00 ERA)

Cubs starting pitcher

Jameson Taillon
(2025: 11-7, 3.68 ERA)

Angels vs Cubs latest injuriesAngels vs Cubs weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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