The San Francisco Giants conclude their series against the San Diego Padres this afternoon from Petco Park.

Taking the mound for the Giants will be right-hander Adrian Houser, making his Giants debut. Houser finished the 2025 season with a 3.31 ERA, 3.81 FIP, with 92 strikeouts to 38 walks in 125 innings pitched between the Chicago White Sox and Tampa Bay Rays.

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He’ll be facing off against Padres right-hander Nick Pivetta, who finished the 2025 season with a 2.87 ERA, 3.49 FIP, with 190 strikeouts to 50 walks in 181.2 innings pitched. His last start was in the Padres’ 8-2 loss to the Detroit Tigers on Thursday, in which he allowed six runs on seven hits with four strikeouts and three walks in three innings.

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Game #6

Who: San Francisco Giants (2-3) vs. San Diego Padres (1-4)

Where: Petco Park, San Diego, California

When: 1:10 p.m. PT

Regional broadcast: NBC Sports Bay Area

National broadcast: n/a

Radio: KNBR 680 AM/104.5 FM, KSFN 1510 AM