The Mariners are -145 favorites vs the Astros

Astros vs Mariners Over / Under today: 7.5 Runs

Astros / Mariners TV Channel: MRTV | SCHN | KING

The Houston Astros (+118) visit T-Mobile Park to take on the Seattle Mariners (-145) on April 10, 2026. First pitch is scheduled for 9:40 pm in Seattle, WA.

This season, the Astros are 6-7 against the spread (ATS), while the Mariners are 4-9 ATS.

Astros vs Mariners Starting Pitchers Today:

Astros starting pitcher: Tatsuya Imai 1-0, 4.50 ERA

Mariners starting pitcher: Emerson Hancock 1-1, 0.73 ERA

Astros vs. Mariners Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneylineAstros+1.5 -190O 7.5 -110+118Mariners -1.5 +155U 7.5 -110-145

Based on recent trends the model predicts the Mariners will win Friday‘s MLB game with 53.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Astros players for Friday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Bets Today:

Christian Walker has hit the Home Runs Over in 6 of his last 9 away games (+18.95 Units / 211% ROI)

Christian Walker has hit the Total Bases Over in 19 of his last 25 away games (+15.70 Units / 57% ROI)

Christian Walker has hit the Hits Over in 21 of his last 25 away games (+15.70 Units / 35% ROI)

Christian Walker has hit the RBIs Over in 10 of his last 15 away games (+9.00 Units / 60% ROI)

Yordan Alvarez has hit the Runs Under in 11 of his last 15 away games (+8.05 Units / 49% ROI)

And here are some favorite MLB player prop bets for Mariners players for Friday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Best Bets Today:

Luke Raley has hit the Home Runs Over in 2 of his last 4 games at home (+13.50 Units / 338% ROI)

Julio Rodriguez has hit the Total Bases Under in 19 of his last 25 games (+11.00 Units / 30% ROI)

Josh Naylor has hit the Hits Under in 15 of his last 25 games (+10.95 Units / 39% ROI)

Josh Naylor has hit the Runs Under in his last 10 games (+10.00 Units / 57% ROI)

J.P. Crawford has hit the Hits Runs and RBIs Under in his last 9 games (+9.85 Units / 84% ROI)

Astros Best Bets Today:

The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 12 of their last 17 games (+6.90 Units / 36% ROI)

The Houston Astros have hit the Game Total Over in 9 of their last 11 games (+6.80 Units / 55% ROI)

The Houston Astros have covered the Run Line in 25 of their last 45 away games (+5.90 Units / 10% ROI)

The Houston Astros have hit the Team Total Over in 8 of their last 11 games (+4.00 Units / 28% ROI)

The Houston Astros have covered the 1st Five Innings (F5) Run Line in 14 of their last 25 away games (+1.40 Units / 5% ROI)

Mariners Best Bets Today:

The Seattle Mariners have hit the Moneyline in 34 of their last 50 games at home (+12.35 Units / 15% ROI)

The Seattle Mariners have hit the 1st Five Innings (F5) Moneyline in 23 of their last 40 games at home (+7.55 Units / 11% ROI)

The Seattle Mariners have hit the Team Total Under in 8 of their last 9 games (+6.70 Units / 61% ROI)

The Seattle Mariners have hit the Game Total Over in 23 of their last 40 games at home (+5.65 Units / 13% ROI)

The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Under in 7 of their last 9 games (+5.00 Units / 51% ROI)

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 6-7 against the Run Line (+0.7 Units / 4.96% ROI).

6-7 when betting on the Moneyline for -4.1 Units / -22.71% ROI

9-4 when betting on the total runs Over for +4.5 Units / 30.82% ROI

4-9 when betting on the total runs Under for -5.7 Units / -40.71% ROI

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 4-9 against the Run Line (-5.6 Units / -36.96% ROI).

4-9 when betting on the Moneyline for -8.4 Units / -46.41% ROI

5-8 when betting on the total runs Over for -3.8 Units / -26.57% ROI

8-5 when betting on the total runs Under for +2.5 Units / 17.48% ROI

Astros Keys to the Game vs. the Mariners

The Astros were 41-8 (.837) when they hit 2 or more home runs in the 2025 season — best in MLB; League Avg: .699.

The Astros were 56-7 (.889) when they scored 5 or more runs in the 2025 season — 3rd best in MLB; League Avg: .797.

The Astros are just 2-126 (.016) when trailing entering the 9th inning since the 2024 season — 2nd lowest in MLB; League Avg: .046.

The Astros are 13-7 (.650) when tied entering the 7th inning since the 2025 season — 4th best in MLB; League Avg: .500.

Mariners Keys to the Game vs. the Astros

The Mariners are just 4-9 (.308) this season — tied for lowest in MLB; League Avg: .500.

The Mariners are just 10-27 (.270) vs top 10 scoring offenses since the 2025 season Today, they face the Astros (second in runs scored).

The Mariners are just 4-8 (.333) when allowing 5 or more extra base hits this season — 2nd lowest in MLB; League Avg: .520.

The Mariners were 70-3 (.959) when leading entering the 8th inning in the 2025 season — best in MLB; League Avg: .909.

Astros Hitting Stats & Trends

The Astros are batting .396 when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Astros hitters have an OBP of .525 (61 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Astros hitters are slugging .750 when facing the starting pitcher for the 3rd time in a game this season — best in MLB.

Astros hitters have an OPS of .900 (140 PA’s) in lefty-lefty matchups since the 2025 season — best in MLB.

Mariners Hitting Stats & Trends

The Mariners are batting just .177 against LHP this season — 3rd lowest in MLB.

Mariners hitters slugged .712 on the first pitch of at-bats in the 2025 season — best in MLB.

The Mariners are batting just .158 on the road this season — lowest in MLB.

Mariners hitters are slugging just .224 against LHP this season — 2nd lowest in MLB.

Astros Pitching Stats & Trends

The Astros have allowed 4.15 runs per game (54/13) in the first 5 innings this season — highest in MLB.

Astros pitchers had a strikeout rate of 46% with two-strikes in the 2025 season — best in MLB.

Astros pitchers have a strikeout rate of 46% with two-strikes since the 2025 season — best in MLB.

Astros pitchers have an ERA of 7.92 (50.0 IP) on the road this season — highest in MLB.

Mariners Pitching Stats & Trends

Mariners pitchers have walked 6% of batters this season — 2nd best in MLB.

Mariners pitchers have thrown at least two strikes in their first three pitches to 71% of opposing batters this season — highest in MLB.

Mariners pitchers have induced opposing hitters to ground into 14 double plays in 60 opportunities (23%) this season — best in MLB.

Mariners pitchers have allowed an OBP of just .267 (3,017 PA’s) when facing the leadoff batter in the inning since the 2024 season — best in MLB.

More MLB Reading:

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