Jose Ramirez and Nathaniel Lowe will be among the star attractions when the Cleveland Guardians play the Washington Nationals on Wednesday at 12:05 p.m. ET, at Nationals Park.

The pitching staff for the Guardians has a collective 8.5 K/9, which ranks 14th in MLB. The Nationals rank 18th in MLB with a .239 team batting average.

Prepare for the Guardians vs. Nationals with what you need to know ahead of Wednesday’s game, including viewing options.

Guardians vs. Nationals: live stream info, TV channel & game timeGame day: Wednesday, May 7, 2025Game time: 12:05 p.m. ETLocation: Washington D.C.Stadium: Nationals ParkTV channel: MASN2 (Washington DC)Live stream: Watch LIVE with Fubo! (Regional restrictions may apply)

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Guardians vs. Nationals odds & betting linesFavorite: Guardians (-132, bet $132 to win $100)Underdog: Nationals (+111, bet $100 to win $111)Over/under: 9

MLB odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 3:07 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.