The Los Angeles Angels (28-32) visit the Boston Red Sox (29-34) for the finale of their 3-game series Wednesday. First pitch from Fenway Park is set for 1:35 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s MLB odds around the VAngels vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Angels lead 2-0

The Angels kicked off the series Monday with a 7-6 win and followed that up with a 4-3 extra-innings victory Tuesday, closing as an underdog in both games. 1B Nolan Schanuel led the way with 2 RBIs in the win on Tuesday. Los Angeles has won 3 of its last 5 games, but is just 3-7 over its last 10 contests. It is 28-32 against the spread (ATS).

The Red Sox have hit a wall and are just 2-8 over their last 10 games, going 0-4 in their last handful at Fenway Park. Boston’s issues have come on the defensive end, allowing 4 or more in 5 of its last 7 games. It is 29-34 ATS.

Angels at Red Sox projected starters

RHP Jose Soriano vs. RHP Lucas Giolito

Soriano (4-5, 3.41 ERA) makes his 13th start. He has a 1.51 WHIP, 4.5 BB/9 and 6.4 K/9 in 68 2/3 innings.

Last start: Win, 6 IP, 0 ER, 4 H, 4 BB, 2 K in 4-1 home win vs. Cleveland Guardians Friday2025 road stats: 4-2, 2.03 ERA (44 1/3 IP, 10 ER), 1.24 WHIP, 5.3 K/9 in 7 starts2024/career vs. Red Sox: 0-1, 9.00 ERA (3 IP, 3 ER), 3 H, 1 BB, 1 K in 1 relief appearance, a 8-6 home loss on April 5

Giolito (1-1, 4.78 ERA) makes his seventh start. He has a 1.44 WHIP, 2.8 BB/9 and 7.3 K/9 in 32 innings.

Last start: No-decision, 4 2/3 IP, 1 ER, 5 H, 2 BB, 3 K in 5-1 home victory vs. the Atlanta Braves Friday2025 home stats: 0-1, 7.36 ERA (14 2/3 IP, 12 ER), 1.98 WHIP, 6.8 K/9 in 3 startsCareer vs. Angels: 4-2, 3.94 ERA (59 1/3 IP, 26 ER), 45 H, 16 BB, 74 K in 10 starts

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Angels at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:09 a.m. ET.

Moneyline (ML): Angels +110 (bet $100 to win $110) | Red Sox -135 (bet $135 to win $100)Run line (RL)/Against the spread (ATS): Angels +1.5 (-190) | Red Sox -1.5 (+155)Over/Under (O/U): 10 (O: -110 | U: -110)Angels at Red Sox picks and predictionsPrediction

Red Sox 4, Angels 3

BET RED SOX (-135).

The Red Sox should avoid the sweep Wednesday as they have yet to be swept at home this season. They are 3-1 in Giolito’s last 4 starts and have allowed just 10 total runs in those contests.

The Angels have been the opposite with Soriano on the mound, going just 2-7 over his last 9 starts. They have scored 2 or fewer in 6 of their last 10 games as well.

Couple all those trends together and back RED SOX (-135).

PASS.

There is no playable moneyline value.

The Angels (-190) are too expensive as a run-line underdog while the Red Sox (+155) might have some value, but are better played on the spread.

BET UNDER 10 (-110).

The Red Sox have gone Under in 8 of their last 10 games and in 4 of Giolito’s last 5 starts.

The Angels are 2-8 O/U in their last 10 games and have gone Under in 3 straight Soriano starts. Back UNDER 10 (-110).

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