The Chicago Cubs (39-24) and Detroit Tigers (42-23) wrap up their 3-game series Sunday. First pitch from Comerica Park in Detroit is set for 1:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Cubs vs. Tigers odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

After losing 3-1 in the series opener on Friday, the Cubs rolled past the Tigers 6-1 on Saturday, hitting 5 home runs and cashing as -111 road favorites. OF Seiya Suzuki led the charge with 2 HRs, while OF Pete Crow-Armstrong, 1B Michael Busch, and 3B Matt Shaw each added one. Chicago will go for its eighth straight series win on Sunday.

The Tigers were limited to just 1 run on 6 hits against SP Jameson Taillon, which helped the Under (8.5) cash for the second straight game. The Tigers’ lone run came on an fielder’s choice by C Jake Rogers. The loss ended Detroit’s 5-game home win streak.

Cubs at Tigers projected starters

RHP Cade Horton vs. RHP Jack Flaherty

Horton (3-0, 3.51 ERA) is making his fifth start and sixth career appearance. He has a 1.21 WHIP, 1.8 BB/9 and 6.7 K/9 in 25 2/3 innings.

Last start: Win, 5 1/3 IP, 1 ER (3 R), 5 H, 1 BB, 3 K in 8-3 road victory against Washington Nationals Tuesday2025 road stats: 2-0, 3.07 ERA (14 2/3 IP, 5 ER), 1.30 WHIP, 6.8 K/9 in 3 games (2 starts)The 23-year-old rookie has never faced the Tigers

Flaherty (4-6, 3.72 ERA) is making his 13th start. He has a 1.09 WHIP, 2.8 BB/9 and 10.5 K/9 in 65 1/3 innings.

Last start: Win, 6 IP, 1 ER, 4 H, 1 BB, 4 K in 13-1 road victory against Chicago White Sox Monday2025 home stats: 2-3, 3.03 ERA (32 2/3 IP, 11 ER), 0.95 WHIP, 12.4 K/9 in 6 startsCareer vs. Cubs: 3-4, 3.67 ERA (68 2/3 IP, 28 ER), 1.22 WHIP, 10.5 K/9 in 17 games (15 starts); last start in 2023

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Cubs at Tigers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 10:49 p.m. ET.

Moneyline (ML): Cubs +120 (bet $100 to win $120) | Tigers -145 (bet $145 to win $100)Run line (RL)/Against the spread (ATS): Cubs +1.5 (-185) | Tigers -1.5 (+150)Over/Under (O/U): 8 (O: -115 | U: -105)Cubs at Tigers picks and predictionsPrediction

Cubs 4, Tigers 2

BET CUBS (+120).

This weekend series featuring 2 division leaders has lived up to the hype. With how evenly matched these teams are, there’s solid value in backing Chicago at +120 on the moneyline. The Cubs own the best road record in baseball at 20-13 and lead the league in road batting average (.274) and road home runs (62). Suzuki has been a force on the road, batting .309 with 12 of his 16 HRs coming away from home. Busch has also thrived on the road, hitting .303 with 8 of his 10 homers coming away from Wrigley.

Given the Cubs’ road success and the value in the number, Chicago looks like the smart play in Sunday’s series finale at Comerica Park.

PASS.

No need to play with the run line when you are getting the Cubs with plus money on the road.

BET UNDER 8 (-105).

The Under has hit in both games of this series and looks like a strong play again Sunday.

The Cubs are 7-2-1 to the Under in their last 10 games, including 4 straight. Detroit has also stayed Under in 3 consecutive games. Flaherty is 2-1-1 to the Under in his last 4 starts, while Horton is 1-1-1 in his last 3. Expect another low-scoring battle.

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