March 30, 2026, 1:51 p.m. ET<\/p>\n
The Los Angeles Angels<\/a> (2-2) and Chicago Cubs<\/a> (1-2) meet Monday at Wrigley Field in Chicago, Illinois. First pitch is slated for 7:40 p.m. ET. Let’s analyze MLB odds around the Angels vs. Cubs odds and make our expert MLB picks and predictions<\/a> for the best bets.<\/p>\n 2025 season series: Chicago 3-0<\/p>\n Los Angeles opened its season with a 2-2 split in a 4-game series at the Houston Astros. Angels pitching allowed just 2 runs over 2 wins to start the series. But on Saturday and Sunday, the Halos coughed up a combined 20 runs in a pair of high-scoring Houston triumphs (11-9 and 9-7).<\/p>\n Chicago remains at home after opening the 2026 campaign with a 3-game Wrigley Field set against the Washington Nationals. The Cubs won Saturday but bracketed that game with Thursday and Sunday losses in a 2-1 Nats series win.<\/p>\n Watch MLB on Fubo!<\/a>Angels at Cubs projected starters<\/p>\n RHP Ryan Johnson vs. RHP Edward Cabrera<\/p>\n Johnson went he went 1-1 with a 7.36 ERA in 2025 with a 1.98 WHIP, 3.1 BB\/9 and 9.8 K\/9 in 14 relief appearances across 14 2\/3 innings.<\/p>\n The 2024 draftee bypassed a minor-league assignment and began his pro career as a member of the Angels bullpen; finished the 2025 season at Single-A Tri-City where he logged a 1.88 ERA in 12 startsRegistered a 3.05 ERA in 20 2\/3 IP in Cactus League ball this springHas never faced the Cubs<\/p>\n Cabrera is making his Cubs debut. Last season, he pitched for the Miami Marlins and went 8-7 with a 3.53 ERA, 1.23 WHIP, 3.1 BB\/9 and 9.8 K\/9 in 26 starts across 137 2\/3 innings.<\/p>\n Struggled in spring training, posting a 7.47 ERA in 5 gamesCareer vs. Angels: 1-0, 2.38 ERA (11 1\/3 IP, 3 ER), 7 H, 6 BB, 15 K in 2 startsAngels at Cubs odds<\/p>\n Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub<\/a> for a full list. Lines last updated at 1:48 p.m. ET.<\/p>\n Moneyline (ML): Angels +150 (bet $100 to win $150) | Cubs -185 (bet $185 to win $100)Run line (RL)\/Against the spread (ATS): Angels +1.5 (-140) | Cubs -1.5 (+115)Over\/Under (O\/U): 9.5 (O: +115 | U: -105)<\/p>\n Slide into: BaseballHQ.com<\/a> for your fantasy baseball news. For decades, BHQ has been helping players just like you win! BHQ offers full-season subscriptions. Sign up today<\/a>!<\/p>\n Angels at Cubs picks and predictionsPrediction<\/p>\n Cubs 6, Angels 4<\/p>\n No interest; PASS.<\/p>\n Chicago has won 4 straight against Los Angeles, outscoring the Angels 24-6 along the way.<\/p>\n The Cubs went 50-31 (.617) at home last season. Including playoff games, the Cubs went 18-9 (.667) from Aug. 16 on.<\/p>\n Last season, Cabrera exhibited an uptick in velocity while posting a career-best walk rate. Over the last 3 seasons for Miami, the 27-year-old has allowed a combined 5 runs across 15 2\/3 IP in his season-debut starts. In 3 career efforts at Wrigley Field, he has held opposing batters to an aggregate .634 OPS.<\/p>\n Johnson is more of a question mark. But notably, his tidy Single-A ERA last season was filed in a pitcher-friendly circuit in the Northwest League.<\/p>\n Preseason projections peg the Cubs as a contender in the NL Central and the Angels as a bottom-feeder in the AL West.<\/p>\n TAKE CHICAGO -1.5 (+115) in this one.<\/p>\n The Over is 13-6-1 across Chicago’s last 20 games at home.<\/p>\n Both bullpens have ERA’s of 3.00, but their early-season figures are loaded with several luck factors. Advanced metrics tell a different story. Plus, neither side figures to be in the best of shape when it comes to availability in the back end of the bullpen.<\/p>\n Add to that a forecast for an outward-blowing breeze at Wrigley, and the OVER 9.5 (-115) is the value side.<\/p>\n For more sports betting picks and tips, check out SportsbookWire.com<\/a> and BetFTW<\/a>.<\/p>\n Follow SportsbookWire on Twitter\/X<\/a> and like us on Facebook<\/a>.<\/p>\n Our team of savvy editors independently handpicks all recommendations. 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