The first MLB matchup on the Friday MLB schedule belongs to the Los Angeles Dodgers and the Washington Nationals. It’s the start of a three-game series that will run through the weekend in the nation’s capital. The Dodgers (4-2) have started the year playing six straight home games, while the Nationals (3-3) have started the season with six straight road games. Emmet Sheehan (0-0, 10.80 ERA) will start for the Dodgers, with Miles Mikolas (0-1, 7.80 ERA) going for the Nationals.<\/p>\n
First pitch is at 1:05 p.m. ET from Nationals Park in Washington, D.C. The latest Dodgers vs. Nationals odds list Los Angeles as the -271 favorite on the money line (risk $271 to win $100). The over\/under for total runs is 9.5. Before making any Nationals vs. Dodgers picks or MLB predictions, see the Dodgers vs. Nationals predictions and betting advice from SportsLine’s proven computer model<\/a>.\u00a0<\/p>\n Visit our\u00a0DraftKings promo code<\/a>\u00a0review to see their latest offers and get started.<\/p>\n The SportsLine Projection Model simulates every MLB game 10,000 times. It was a profitable 35-29 on top-rated MLB money-line picks last season. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following its\u00a0MLB betting<\/a>\u00a0picks at\u00a0sportsbooks<\/a>\u00a0and on\u00a0betting sites<\/a>\u00a0could have seen strong returns.<\/p>\n Now, the model has set its sights on Dodgers vs. Nationals<\/a> and just locked in its picks and MLB predictions.\u00a0You can head to SportsLine now to see the model’s picks<\/a>. Here are several\u00a0MLB odds<\/a>\u00a0and betting lines for Dodgers vs. Nationals:<\/p>\n Dodgers vs. Nationals money line<\/p>\n Dodgers -271, Nationals +218<\/p>\n Dodgers vs. Nationals over\/under<\/p>\n 9.5 runs<\/p>\n Dodgers vs. Nationals run line\u00a0<\/p>\n Nationals +1.5 (-218)<\/p>\n Dodgers vs. Nationals picks<\/p>\n See picks at SportsLine<\/a><\/p>\n Dodgers vs. Nationals streaming\u00a0<\/p>\n Fubo<\/a> (Try for free)<\/p>\n Visit our\u00a0Kalshi promo code<\/a>\u00a0review to see their latest offers and get started.<\/p>\n Top Dodgers vs. Nationals predictions\u00a0<\/p>\n After 10,000 simulations of Dodgers vs. Nationals, the model is going Over 9.5 total runs.\u00a0Four of the Nationals’ first six games this season have gone over the total. The total has gone over in six of the Nationals’ last six games against the Dodgers. The total has gone over in four of the Dodgers’ last five games when playing on the road against the Nationals.<\/p>\n The model has taken into account the effectiveness of both starters in forecasting a high-scoring game. Sheehan gave up four earned runs on five hits in his first start, and he added six strikeouts in 3.1 innings. Meanwhile, Mikolas has a 7.20 ERA to start the 2026 season. He allowed four runs on six hits over five innings, striking out four. The model’s 10,000 simulations project 9.6 total runs being scored.\u00a0Get the Dodgers vs. Nationals money-line pick at SportsLine<\/a>.<\/p>\n How to make Dodgers vs. Nationals picks<\/p>\n After simulating every pitch of Dodgers vs. Nationals 10,000 times, the model also says one side of the money line has all the value. You can get that pick at SportsLine<\/a>.\u00a0<\/p>\n