{"id":663117,"date":"2026-04-04T17:37:17","date_gmt":"2026-04-04T17:37:17","guid":{"rendered":"https:\/\/www.rawchili.com\/mlb\/663117\/"},"modified":"2026-04-04T17:37:17","modified_gmt":"2026-04-04T17:37:17","slug":"cubs-vs-guardians-prediction-picks-odds-for-tonights-mlb-game","status":"publish","type":"post","link":"https:\/\/www.rawchili.com\/mlb\/663117\/","title":{"rendered":"Cubs vs Guardians Prediction, Picks &#038; Odds for Tonight&#8217;s MLB Game"},"content":{"rendered":"<p>Want to get more Covers content? Add us as a <a href=\"https:\/\/www.google.com\/preferences\/source?q=covers.com\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:preferred source on your Google account here;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;preferred source on your Google account here&quot;}\" class=\"link \">preferred source on your Google account here<\/a>.<\/p>\n<p>The Chicago Cubs and Cleveland Guardians play the second of a three-game set at Progressive Field tonight.<\/p>\n<p>Although Chicago fell 4-1 on Friday, my Cubs vs. Guardians predictions are backing the visitors to bounce back.<\/p>\n<p>Advertisement<\/p>\n<p>Here are my top free\u00a0<a href=\"https:\/\/www.covers.com\/picks\/mlb\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:MLB picks;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;MLB picks&quot;}\" class=\"link \">MLB picks<\/a> for this interleague showdown on Saturday, April 4.<\/p>\n<p>Who will win Cubs vs Guardians today: Cubs moneyline (-126)<\/p>\n<p>The\u00a0<a href=\"https:\/\/www.covers.com\/sport\/baseball\/mlb\/teams\/main\/cleveland-guardians\/odds\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:Cleveland Guardians;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;Cleveland Guardians&quot;}\" class=\"link \">Cleveland Guardians<\/a> are sending <a href=\"https:\/\/www.covers.com\/sport\/baseball\/mlb\/players\/196639\/slade-cecconi\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:Slade Cecconi;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;Slade Cecconi&quot;}\" class=\"link \">Slade Cecconi<\/a> to the mound after he surrendered six runs in 4 1\/3 innings in his season debut. He posted a 4.99 xERA in 2025 and ranked second-worst in barrel rate and hard-hit rate among pitchers with at least 100 innings of work.<\/p>\n<p>On the other side, the <a href=\"https:\/\/www.covers.com\/sport\/baseball\/mlb\/teams\/main\/chicago-cubs\/odds\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:Chicago Cubs;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;Chicago Cubs&quot;}\" class=\"link \">Chicago Cubs<\/a> respond with southpaw <a href=\"https:\/\/www.covers.com\/sport\/baseball\/mlb\/players\/291851\/shota-imanaga\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:Shota Imanaga;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;Shota Imanaga&quot;}\" class=\"link \">Shota Imanaga<\/a>, who pitched to a 3.73 ERA with a 0.99 WHIP last year.<\/p>\n<p>Both teams are struggling at the dish, but the Cubs were significantly more productive last year. They also lead the majors in hard-hit rate, while the Guardians are 27th.<\/p>\n<p><img alt=\"Covers\" loading=\"lazy\" width=\"25\" height=\"25\" decoding=\"async\" data-nimg=\"1\" class=\"standard-img\" style=\"color:transparent\" src=\"https:\/\/www.rawchili.com\/mlb\/wp-content\/uploads\/2026\/03\/f0a27353005c469f1dfd7a37c508069d.jpeg\"\/><\/p>\n<p>Covers<\/p>\n<p> COVERS INTEL:<\/p>\n<p>Cleveland batted just .224 against lefties last year, while Imanaga flashed an impressive .218 OBA in 25 starts.<\/p>\n<p>Advertisement<\/p>\n<p>Cubs vs Guardians Over\/Under pick: Over 7.5 (-120)<\/p>\n<p><a href=\"https:\/\/www.covers.com\/sport\/baseball\/mlb\/players\/194691\/pete-crow-armstrong\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:Pete Crow-Armstrong;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;Pete Crow-Armstrong&quot;}\" class=\"link \">Pete Crow-Armstrong<\/a> and <a href=\"https:\/\/www.covers.com\/sport\/baseball\/mlb\/players\/228602\/michael-busch\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:Michael Bush;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;Michael Bush&quot;}\" class=\"link \">Michael Bush<\/a> are slugging just .308 and .320, respectively, this season. That said, Bush has an xSLG of .548, while PCA\u2019s sits at .475. These big hitters are due for a breakout, and Cecconi could be the perfect pitcher to exploit.<\/p>\n<p>While Imanaga is marginally better than Cecconi, he also tends to get hit hard. The southpaw allowed 1.9 home runs per nine innings in 2025 and gave up four runs in his season debut.<\/p>\n<p>With both starters struggling and the wind blowing towards the outfield at 12 mph this evening, the total is too low at 7.5.<\/p>\n<p>Advertisement<\/p>\n<p>Rohit&#8217;s MLB 2026 Transparency Record<\/p>\n<p>ML\/RL bets: 3-2, +0.3 units<\/p>\n<p>Over\/Under bets: 1-0, +1 units<\/p>\n<p>Cubs vs Guardians odds<\/p>\n<p>Moneyline: Chicago -126 | Cleveland +117<\/p>\n<p>Run line: Chicago -1.5 (+138) | Cleveland +1.5 (-144)<\/p>\n<p>Over\/Under: Over 7.5 (-120) | Under 7.5 (+113)<\/p>\n<p>Cubs vs Guardians trend<\/p>\n<p>Chicago has hit the F5 team total Over in 30 of its last 46 games (+11.35 Units \/ 20% ROI). Find more\u00a0<a href=\"https:\/\/www.covers.com\/sport\/baseball\/mlb\/matchup\/369352\/picks#trends\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:MLB betting trends;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;MLB betting trends&quot;}\" class=\"link \">MLB betting trends<\/a> for Cubs vs. Guardians.<\/p>\n<p>How to watch Cubs vs Guardians and game info<\/p>\n<p>Location<\/p>\n<p>Progressive Field, Cleveland, OH<\/p>\n<p>Date<\/p>\n<p>Saturday, April 4, 2026<\/p>\n<p>First pitch<\/p>\n<p>7:15 p.m. ET<\/p>\n<p>TV<\/p>\n<p>FOX<\/p>\n<p>Cubs starting pitcher<\/p>\n<p>Shota Imanaga<br \/>(0-1, 7.20 ERA)<\/p>\n<p>Guardians starting pitcher<\/p>\n<p>Slade Cecconi<br \/>(0-1, 12.46 ERA)<\/p>\n<p>Cubs vs Guardians latest injuriesCubs vs Guardians weather<\/p>\n<p>Odds are correct at the time of publishing and are subject to change.<br \/>Not intended for use in MA.<br \/>Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.<\/p>\n<p>Advertisement<\/p>\n<p>This article originally appeared on <a href=\"https:\/\/www.covers.com\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:Covers.com;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;Covers.com&quot;}\" class=\"link \">Covers.com<\/a>, read the full article <a href=\"https:\/\/www.covers.com\/mlb\/cubs-vs-guardians-prediction-picks-odds-saturday-4-4-2026\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:here;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;here&quot;}\" class=\"link \">here<\/a> and view our <a href=\"https:\/\/www.covers.com\/betting\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:best betting sites;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;best betting sites&quot;}\" class=\"link \">best betting sites<\/a> or check out our top <a href=\"https:\/\/www.covers.com\/betting\/bonuses\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:sportsbook promos;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;sportsbook promos&quot;}\" class=\"link \">sportsbook promos<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"Want to get more Covers content? Add us as a preferred source on your Google account here. The&hellip;\n","protected":false},"author":2,"featured_media":663118,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2399],"tags":[5,138,24,4245,135,51,161,47167,4,35,667,770,9113],"class_list":{"0":"post-663117","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-chicago-cubs","8":"tag-baseball","9":"tag-chicago","10":"tag-chicago-cubs","11":"tag-chicagocubs","12":"tag-cleveland","13":"tag-cleveland-guardians","14":"tag-cubs","15":"tag-michael-bush","16":"tag-mlb","17":"tag-pete-crow-armstrong","18":"tag-progressive-field","19":"tag-shota-imanaga","20":"tag-slade-cecconi"},"share_on_mastodon":{"url":"https:\/\/channels.im\/@mlb\/116347658382527104","error":""},"_links":{"self":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/posts\/663117","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/comments?post=663117"}],"version-history":[{"count":0,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/posts\/663117\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/media\/663118"}],"wp:attachment":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/media?parent=663117"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/categories?post=663117"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/tags?post=663117"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}