{"id":680368,"date":"2026-04-21T13:57:26","date_gmt":"2026-04-21T13:57:26","guid":{"rendered":"https:\/\/www.rawchili.com\/mlb\/680368\/"},"modified":"2026-04-21T13:57:26","modified_gmt":"2026-04-21T13:57:26","slug":"white-sox-vs-diamondbacks-prediction-odds-player-prop-bets-today","status":"publish","type":"post","link":"https:\/\/www.rawchili.com\/mlb\/680368\/","title":{"rendered":"White Sox vs Diamondbacks Prediction, Odds &#038; Player Prop Bets Today"},"content":{"rendered":"<p>The Diamondbacks are -160 favorites vs the White Sox<\/p>\n<p>White Sox vs Diamondbacks Over \/ Under today: 9 Runs<\/p>\n<p>White Sox \/ Diamondbacks TV Channel: CHSN | DBTV<\/p>\n<p>The Chicago White Sox (+135) visit Chase Field to take on the Arizona Diamondbacks (-160) on April 21, 2026. First pitch is scheduled for 9:40 pm in Phoenix, AZ.<\/p>\n<p>This season, the White Sox are 8-14 against the spread (ATS), while the Diamondbacks are 17-5 ATS.<\/p>\n<p>White Sox vs Diamondbacks Starting Pitchers Today:<\/p>\n<p>White Sox starting pitcher: Sean Burke 0-2, 4.43 ERA<\/p>\n<p>Diamondbacks starting pitcher: Merrill Kelly 1-0, 3.38 ERA<\/p>\n<p>White Sox vs. Diamondbacks Odds, Run Line, Over\/Under &amp; Moneyline <\/p>\n<p>SpreadOver \/ UnderMoneylineWhite Sox+1.5   -165O 9   +100+135Diamondbacks -1.5   +135U 9   -120-160<\/p>\n<p>Based on recent trends the model predicts the Diamondbacks will win Tuesday\u2018s MLB game with 57.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.<\/p>\n<p class=\"has-text-align-center\">Bet now on White Sox vs Diamondbacks and all games with BetMGM<\/p>\n<p>We\u2019ve highlighted some favorite MLB player prop bets for White Sox players for Tuesday\u2018s game, looking at profitable historical betting trends:<\/p>\n<p>Best White Sox Player Prop Bets Today:<\/p>\n<p>Munetaka Murakami has hit the Home Runs Over in 4 of his last 6 games (+14.00 Units \/ 233% ROI)<\/p>\n<p>Edgar Quero has hit the Runs Under in his last 10 games (+10.00 Units \/ 44% ROI)<\/p>\n<p>Colson Montgomery has hit the Singles Under in 13 of his last 15 games (+8.75 Units \/ 33% ROI)<\/p>\n<p>Miguel Vargas has hit the Walks Over in 14 of his last 25 games (+8.70 Units \/ 35% ROI)<\/p>\n<p>Chase Meidroth has hit the Hits Under in 12 of his last 20 away games (+7.60 Units \/ 28% ROI)<\/p>\n<p>And here are some favorite MLB player prop bets for Diamondbacks players for Tuesday\u2018s game, looking at profitable historical betting trends:<\/p>\n<p>Best Diamondbacks Player Prop Best Bets Today:<\/p>\n<p>Ildemaro Vargas has hit the Hits Over in his last 15 games (+15.00 Units \/ 52% ROI)<\/p>\n<p>Alek Thomas has hit the Singles Under in 17 of his last 20 games (+12.65 Units \/ 40% ROI)<\/p>\n<p>Ildemaro Vargas has hit the Runs Over in 8 of his last 10 games (+10.65 Units \/ 107% ROI)<\/p>\n<p>Jose Fernandez has hit the Home Runs Over in 1 of his last 7 games at home (+10.00 Units \/ 143% ROI)<\/p>\n<p>Ildemaro Vargas has hit the Total Bases Over in 11 of his last 15 games (+8.95 Units \/ 45% ROI)<\/p>\n<p>White Sox Best Bets Today:<\/p>\n<p>The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 31 of their last 50 away games (+8.20 Units \/ 13% ROI)<\/p>\n<p>The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 14 of their last 25 games (+6.70 Units \/ 26% ROI)<\/p>\n<p>The Chicago White Sox have hit the Game Total Over in 16 of their last 25 games (+6.10 Units \/ 22% ROI)<\/p>\n<p>The Chicago White Sox have hit the Team Total Over in 29 of their last 50 away games (+6.00 Units \/ 10% ROI)<\/p>\n<p>The Chicago White Sox have hit the Moneyline in 23 of their last 50 away games (+4.10 Units \/ 8% ROI)<\/p>\n<p>Diamondbacks Best Bets Today:<\/p>\n<p>The Arizona Diamondbacks have hit the Team Total Over in 34 of their last 50 games (+17.90 Units \/ 32% ROI)<\/p>\n<p>The Arizona Diamondbacks have covered the Run Line in 34 of their last 50 games (+12.70 Units \/ 18% ROI)<\/p>\n<p>The Arizona Diamondbacks have hit the 1st Five Innings (F5) Moneyline in 26 of their last 45 games at home (+11.90 Units \/ 20% ROI)<\/p>\n<p>The Arizona Diamondbacks have hit the Moneyline in 23 of their last 35 games at home (+10.40 Units \/ 24% ROI)<\/p>\n<p>The Arizona Diamondbacks have hit the 1st Five Innings (F5) Team Total Under in 15 of their last 20 games at home (+9.10 Units \/ 37% ROI)<\/p>\n<p>White Sox Against the Spread (ATS) Record<\/p>\n<p>Against the spread this season, the White Sox are 10-12 against the Run Line (-7.95 Units \/ -24.96% ROI).<\/p>\n<p>8-14 when betting on the Moneyline for -2.8 Units \/ -12.67% ROI<\/p>\n<p>14-8 when betting on the total runs Over for +5.1 Units \/ 21.07% ROI<\/p>\n<p>8-14 when betting on the total runs Under for -7.5 Units \/ -30.99% ROI<\/p>\n<p>Diamondbacks Against the Spread (ATS) Record<\/p>\n<p>Against the spread this season, the Diamondbacks are 17-5 against the Run Line (+10.15 Units \/ 31.47% ROI).<\/p>\n<p>13-9 when betting on the Moneyline for +6.05 Units \/ 25.53% ROI<\/p>\n<p>13-8 when betting on the total runs Over for +4.3 Units \/ 17.62% ROI<\/p>\n<p>8-13 when betting on the total runs Under for -6 Units \/ -25% ROI<\/p>\n<p>\t\t\tDiamondbacks vs White Sox Home Run Prop Bets Today\t\t\t<\/p>\n<p>\t\t\t\t\t\tYes<\/p>\n<p>\t\t\t\t\t\tMunetaka Murakami<\/p>\n<p>\t\t\t\t\t\t<a href=\"https:\/\/sports.betmgm.com\/en\/sports\/baseball-23\/betting\/usa-9\/mlb-75\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">+310<\/a><\/p>\n<p>\t\t\t\t\t\tKetel Marte<\/p>\n<p>\t\t\t\t\t\t<a href=\"https:\/\/sports.betmgm.com\/en\/sports\/baseball-23\/betting\/usa-9\/mlb-75\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">+375<\/a><\/p>\n<p>\t\t\t\t\t\tCorbin Carroll<\/p>\n<p>\t\t\t\t\t\t<a href=\"https:\/\/sports.betmgm.com\/en\/sports\/baseball-23\/betting\/usa-9\/mlb-75\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">+425<\/a><\/p>\n<p>\t\t\t\t\t\tColson Montgomery<\/p>\n<p>\t\t\t\t\t\t<a href=\"https:\/\/sports.betmgm.com\/en\/sports\/baseball-23\/betting\/usa-9\/mlb-75\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">+425<\/a><\/p>\n<p>\t\t\t\t\t\tAdrian Del Castillo<\/p>\n<p>\t\t\t\t\t\t<a href=\"https:\/\/sports.betmgm.com\/en\/sports\/baseball-23\/betting\/usa-9\/mlb-75\" rel=\"noreferrer nofollow noopener\" target=\"_blank\">+550<\/a><\/p>\n<p>\t\t\tDiamondbacks vs White Sox Total Hits Prop Bets Today\t\t\t<\/p>\n<p>\t\t\tDiamondbacks vs White Sox Strikeout Prop Bets Today\t\t\t<\/p>\n<p>White Sox Keys to the Game vs. the Diamondbacks<\/p>\n<p>The White Sox are just 87-41 (.680) when leading entering the 7th inning since the 2024 season \u2014 lowest in MLB; League Avg: .866.<\/p>\n<p>The White Sox are just 54-18 (.750) when leading entering the 7th inning since the 2025 season \u2014 lowest in MLB; League Avg: .874.<\/p>\n<p>The White Sox are just 62-7 (.899) when leading entering the 9th inning since the 2025 season \u2014 lowest in MLB; League Avg: .955.<\/p>\n<p>The White Sox are just 11-105 (.095) when allowing 10 or more hits since the 2024 season \u2014 lowest in MLB; League Avg: .251.<\/p>\n<p>Diamondbacks Keys to the Game vs. the White Sox<\/p>\n<p>The Diamondbacks are 3-4 (.429) when trailing entering the 7th inning this season \u2014 best in MLB; League Avg: .133.<\/p>\n<p>The Diamondbacks are just 69-20 (.775) when leading entering the 7th inning since the 2025 season \u2014 2nd lowest in MLB; League Avg: .874.<\/p>\n<p>The Diamondbacks were just 67-7 (.905) when leading entering the 9th inning in the 2025 season \u2014 2nd lowest in MLB; League Avg: .956.<\/p>\n<p>The Diamondbacks are 2-5 (.286) when trailing entering the 8th inning this season \u2014 tied for best in MLB; League Avg: .107.<\/p>\n<p>White Sox Hitting Stats &amp; Trends<\/p>\n<p>The White Sox have a winning percentage of just 32%  since the 2024 season \u2014 lowest in MLB.<\/p>\n<p>The White Sox won only 33% of their road games in the 2025 season \u2014 tied for 2nd lowest in MLB.<\/p>\n<p>White Sox hitters have an OPS of just .510 (251 PA\u2019s) in innings 7-9 this season \u2014 lowest in MLB.<\/p>\n<p>The White Sox have a winning percentage of just 29% on the road since the 2024 season \u2014 2nd lowest in MLB.<\/p>\n<p>Diamondbacks Hitting Stats &amp; Trends<\/p>\n<p>The Diamondbacks are batting .270 against LHP since the 2024 season \u2014 best in MLB.<\/p>\n<p>Diamondbacks hitters have chased 49% of pitches out of the zone with two-strikes this season \u2014 highest in MLB.<\/p>\n<p>Diamondbacks hitters struck out in just 19% of their PA\u2019s against LHP in the 2025 season \u2014 3rd best in MLB.<\/p>\n<p>The Diamondbacks are batting .284 against LHP this season \u2014 tied for 2nd best in MLB.<\/p>\n<p>White Sox Pitching Stats &amp; Trends<\/p>\n<p>The White Sox have won just 15% of games in which their opponents scored first  since the 2024 season \u2014 lowest in MLB.<\/p>\n<p>Opponents have a miss rate of just 22% against White Sox pitchers  this season \u2014 2nd lowest in MLB.<\/p>\n<p>The White Sox have won just 9% of road games in which their opponents scored first since the 2024 season \u2014 lowest in MLB.<\/p>\n<p>In games when their opponents have scored three or more runs in an inning, the White Sox won just 10% of the time  since the 2024 season \u2014 lowest in MLB.<\/p>\n<p>Diamondbacks Pitching Stats &amp; Trends<\/p>\n<p>Diamondbacks pitchers have allowed an OBP of just .250 (196 PA\u2019s) when facing the leadoff batter in the inning this season \u2014 2nd best in MLB.<\/p>\n<p>Diamondbacks pitchers have walked 8% of batters  this season \u2014 5th best in MLB.<\/p>\n<p>Diamondbacks pitchers have a strikeout rate of just 20%  this season \u2014 tied for 4th lowest in MLB.<\/p>\n<p>Diamondbacks pitchers have walked 4% of batters when facing the leadoff batter in the inning this season \u2014 best in MLB.<\/p>\n<p>More MLB Reading:<\/p>\n<p class=\"has-text-align-center\">Bet now on White Sox vs Diamondbacks and all games with BetMGM<\/p>\n<p>Bet on MLB Odds at BetMGM<\/p>\n<p><a href=\"https:\/\/sports.betmgm.com\/en\/blog\/latest-sports-betting-promotions-offers-betmgm-2\/\" rel=\"nofollow noopener\" target=\"_blank\">Sportsbook promos<\/a> are always available at <a href=\"https:\/\/www.betmgm.com\/en\/sports?pid=direct&amp;af_sub1=7071077&amp;wm=7071077&amp;tdpeh=BetMGM&amp;utm_source=seo&amp;utm_medium=content&amp;utm_campaign=jarvis\" rel=\"nofollow noopener\" target=\"_blank\">BetMGM<\/a>. For new customers, check out the <a href=\"https:\/\/sports.betmgm.com\/en\/blog\/best-bonus-code\/\" rel=\"nofollow noopener\" target=\"_blank\">sportsbook welcome offer<\/a> and <a href=\"http:\/\/betmgm.com\/refer-a-friend-sports\" rel=\"nofollow noopener\" target=\"_blank\">BetMGM Refer a Friend<\/a>. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.<\/p>\n","protected":false},"excerpt":{"rendered":"The Diamondbacks are -160 favorites vs the White Sox White Sox vs Diamondbacks Over \/ Under today: 9&hellip;\n","protected":false},"author":2,"featured_media":664654,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2404],"tags":[146,22,4314,5,38,4],"class_list":{"0":"post-680368","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-arizona-diamondbacks","8":"tag-arizona","9":"tag-arizona-diamondbacks","10":"tag-arizonadiamondbacks","11":"tag-baseball","12":"tag-diamondbacks","13":"tag-mlb"},"share_on_mastodon":{"url":"https:\/\/channels.im\/@mlb\/116443050754397743","error":""},"_links":{"self":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/posts\/680368","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/comments?post=680368"}],"version-history":[{"count":0,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/posts\/680368\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/media\/664654"}],"wp:attachment":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/media?parent=680368"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/categories?post=680368"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/tags?post=680368"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}