{"id":680858,"date":"2026-04-22T07:24:25","date_gmt":"2026-04-22T07:24:25","guid":{"rendered":"https:\/\/www.rawchili.com\/mlb\/680858\/"},"modified":"2026-04-22T07:24:25","modified_gmt":"2026-04-22T07:24:25","slug":"st-louis-cardinals-vs-miami-marlins-prediction-pick-for-mlb-on-wednesday-4-22-26","status":"publish","type":"post","link":"https:\/\/www.rawchili.com\/mlb\/680858\/","title":{"rendered":"St. Louis Cardinals vs. Miami Marlins prediction, pick for MLB on Wednesday 4\/22\/26"},"content":{"rendered":"<p data-kb-block=\"kb-adv-heading151976_e554f3-7c\">Brendan O\u2019Sullivan dives into his pick and prediction for the St. Louis Cardinals vs. Miami Marlins game on Wednesday, April 22.<\/p>\n<p>The Cardinals and Marlins play the final game of their three-game series on Wednesday, April 22.<\/p>\n<p>Miami is a -131 moneyline favorite, while St. Louis is +109 on <a href=\"https:\/\/sportsbook.draftkings.com\/leagues\/baseball\/mlb\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">DraftKings Sportsbook<\/a>. The game total is set at over\/under 8.5 runs.<\/p>\n<p>Let\u2019s get into a pick and prediction for this Cardinals vs. Marlins game.<\/p>\n<p>Cardinals vs. Marlins prediction, preview<\/p>\n<p>The NL Central has five teams above .500. When\u2019s the last time that\u2019s happened? Sure, it\u2019s early in the season, but it\u2019s a surprisingly good start for a few teams. The Cardinals are expected to be one of the weakest teams in the majors this season, but their young core is shining thus far.<\/p>\n<p>Jordan Walker is the obvious standout, but players like JJ Wetherholt, Alec Burleson, Ivan Herrera, Masyn Winn and Nolan Gorman are all contributors in the lineup. Let\u2019s be clear, though, this roster is unlikely to reach the playoffs. It is, however, capable of stringing together wins when the batters are hot.<\/p>\n<p>The pitching hasn\u2019t been terrific, besides closer Riley O\u2019Brien. Kyle Leahy is Wednesday\u2019s starter, posting a 5.21 ERA through 19.0 innings and four starts. He\u2019s allowed 21 hits, 11 earned runs and eight walks while striking out 13 batters this season.<\/p>\n<p>It\u2019s likely the Marlins\u2019 offense capitalizes on this pitching matchup. Miami ranks 13th in runs per game and will need to score to support Janson Junk, who has a 4.50 ERA through 22.0 innings. He\u2019s allowed 23 hits, 11 earned runs and six walks while striking out 15 batters through four starts.<\/p>\n<p>Offense should be at the forefront as neither starter has limited base runners this season.<\/p>\n<p>Cardinals vs. Marlins Pick, Best Bet<\/p>\n<p>Rather than choosing a side, I\u2019m all in for an offensive showing. Both starters are struggling this season, so it will likely come down to who scores more.<\/p>\n<p><a href=\"https:\/\/sportsbook.draftkings.com\/event\/stl-cardinals-%2540-mia-marlins\/34027866\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Best Bet: Over 8.5 runs (-112)<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Brendan O\u2019Sullivan dives into his pick and prediction for the St. Louis Cardinals vs. Miami Marlins game on&hellip;\n","protected":false},"author":2,"featured_media":680859,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2403],"tags":[5,160,4,3719,673,67,4311,4310],"class_list":{"0":"post-680858","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-st-louis-cardinals","8":"tag-baseball","9":"tag-cardinals","10":"tag-mlb","11":"tag-rail","12":"tag-st-louis","13":"tag-st-louis-cardinals","14":"tag-stlouis","15":"tag-stlouiscardinals"},"share_on_mastodon":{"url":"https:\/\/channels.im\/@mlb\/116447167374813824","error":""},"_links":{"self":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/posts\/680858","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/comments?post=680858"}],"version-history":[{"count":0,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/posts\/680858\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/media\/680859"}],"wp:attachment":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/media?parent=680858"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/categories?post=680858"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/tags?post=680858"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}