{"id":681189,"date":"2026-04-22T17:30:16","date_gmt":"2026-04-22T17:30:16","guid":{"rendered":"https:\/\/www.rawchili.com\/mlb\/681189\/"},"modified":"2026-04-22T17:30:16","modified_gmt":"2026-04-22T17:30:16","slug":"dodgers-vs-giants-prediction-odds-probable-pitchers-prop-bets-for-wednesday-april-22","status":"publish","type":"post","link":"https:\/\/www.rawchili.com\/mlb\/681189\/","title":{"rendered":"Dodgers vs. Giants Prediction, Odds, Probable Pitchers, Prop Bets for Wednesday, April 22"},"content":{"rendered":"<p id=\"inline-text-0\" class=\"mt-[18px] md:mt-0 mb-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"76\">Shohei Ohtani takes the mound as the Los Angeles Dodgers look to get back on track against the San Francisco Giants on Wednesday night.<\/p>\n<p id=\"inline-text-1\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"79\">The Giants upset Yoshinobu Yamamoto with a 3-1 win in the series opener, handing the Dodgers their third loss in the last four games.<\/p>\n<p id=\"inline-text-2\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"7c\">Here are the odds, probable pitchers, and predictions for Dodgers vs. Giants on Wednesday, April 22.<\/p>\n<p>Dodgers vs. Giants Odds, Run Line and Total<\/p>\n<p id=\"inline-text-4\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"7i\"><a href=\"http:\/\/bit.ly\/4kJjtBu\" rel=\"nofollow sponsored noopener\" target=\"_blank\">Odds via DraftKings Sportsbook<\/a><\/p>\n<p id=\"inline-text-5\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"7l\">Run Line<\/p>\n<p>Dodgers -1.5 (-126)Giants +1.5 (+104)<\/p>\n<p id=\"inline-text-7\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"7r\">Moneyline<\/p>\n<p id=\"inline-text-9\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"7x\">Total<\/p>\n<p>8.0 (Over -102\/Under -118)Dodgers vs. Giants Probable PitchersDodgers: Shohei Ohtani (2-0, 0.50 ERA)Giants: Tyler Mahle (0-3, 7.23 ERA)Dodgers vs. Giants How to WatchDate: Wednesday, April 22Time: 9:45 p.m. ETVenue: Oracle ParkHow to Watch (TV): SNLA, NBCSBADodgers record: 16-7Giants record: 10-13Dodgers vs. Giants Best MLB Prop BetsDodgers Best MLB Prop BetShohei Ohtani UNDER 4.5 Hits Allowed (-150)<\/p>\n<p id=\"inline-text-18\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"8o\">Shohei Ohtani has been nearly untouchable on the mound so far this season. He\u2019s allowed just two runs (one earned) on seven hits across 18 innings in three starts.<\/p>\n<p id=\"inline-text-19\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"8r\">Ohtani made one appearance against the Giants last season, allowing one hit on 36 pitches in three innings. He should silence the Giants bats again tonight, and honestly, is worth a look in the NL Cy Young Award market as well.<\/p>\n<p>Dodgers vs. Giants Prediction and Pick<\/p>\n<p id=\"inline-text-21\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"8x\">With a pitching matchup of Ohtani vs. Mahle, I don\u2019t think this line is nearly high enough for the Dodgers.<\/p>\n<p id=\"inline-text-22\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"90\">Mahle allowed 8 runs on 8 hits in 4 innings last time out, and also got roughed up by the Mets for 5 runs on 8 hits earlier this month.<\/p>\n<p id=\"inline-text-23\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"93\">The Dodgers will flex their muscles and get back on track in a big way tonight.<\/p>\n<p id=\"inline-text-24\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"96\">Pick: Dodgers -1.5 (-126)<\/p>\n<p id=\"inline-text-26\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"9b\">Unlock $300 in bonus bets \u2014 all without a <a href=\"https:\/\/www.si.com\/betting\/sportsbook-promos\/draftkings-promo-code\" rel=\"nofollow noopener\" target=\"_blank\">promo code for DraftKings<\/a>. Sign up and place a $5 bet and you will receive <a href=\"http:\/\/bit.ly\/4kJjtBu\" rel=\"nofollow sponsored noopener\" target=\"_blank\">$300 in bonus bets <\/a>if that first bet wins.\u00a0<\/p>\n<p id=\"inline-text-27\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"9e\">Odds refresh periodically and are subject to change.<\/p>\n<p id=\"inline-text-28\" class=\"my-[18px] [&amp;_a]:text-primary my-f-1.5\" q:key=\"0\" q:id=\"9h\">If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"22\" height=\"22\" alt=\"\" src=\"https:\/\/assets.minutemediacdn.com\/platform\/google_discover_icon.svg\" class=\"shrink-0\"\/>Add us as a preferred source on Google<a aria-label=\"Follow si.com on Google News\" href=\"https:\/\/www.google.com\/preferences\/source?q=si.com\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" class=\"flex h-[30px] w-[30px] shrink-0 items-center justify-center rounded-full bg-primary font-group-large text-sm font-medium text-white transition-colors hover:bg-secondary focus:bg-secondary md:w-auto md:gap-2.5 md:px-4 md:py-[5px]\">Follow<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Shohei Ohtani takes the mound as the Los Angeles Dodgers look to get back on track against the&hellip;\n","protected":false},"author":2,"featured_media":681190,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2408],"tags":[5,162,4,378,66,4343,4340,4344,4341,4342],"class_list":{"0":"post-681189","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-san-francisco-giants","8":"tag-baseball","9":"tag-giants","10":"tag-mlb","11":"tag-san-francisco","12":"tag-san-francisco-giants","13":"tag-sanfrancisco","14":"tag-sanfranciscogiants","15":"tag-sf","16":"tag-sf-giants","17":"tag-sfgiants"},"share_on_mastodon":{"url":"https:\/\/channels.im\/@mlb\/116449551186802300","error":""},"_links":{"self":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/posts\/681189","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/comments?post=681189"}],"version-history":[{"count":0,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/posts\/681189\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/media\/681190"}],"wp:attachment":[{"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/media?parent=681189"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/categories?post=681189"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rawchili.com\/mlb\/wp-json\/wp\/v2\/tags?post=681189"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}