The Chicago Bulls play the Detroit Pistons at United Center on Wednesday, October 22, 2025. The game, the first of the 2025-26 season for both teams, tips at 8 p.m. ET on CHSN and FDSDET.

The Pistons are only a 2-point favorite when they and the Bulls square off in a game projected to be a close matchup. The game’s over/under is set at 234.5.

Pistons vs. Bulls betting odds

NBA odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 3:29 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread: Detroit -2Total: 234.5Moneyline: Detroit -138, Chicago +117

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Pistons at Bulls odds, spread, & morePredictionPick ATS: Bulls (+ 2)Pick OU:
Under (234.5)Prediction:
Pistons 117 – Bulls 116MoneylineThe Pistons were favored on the moneyline 40 total times last season. They went 26-14 in those games.Detroit had a record of 22-10 when playing as a moneyline favorite with odds of -138 or shorter last year (68.8%).The Pistons have an implied moneyline win probability of 58.0% in this matchup.Chicago was underdogs in 59 games last season and won 25 (42.4%) of those contests.The Bulls were 20-32 last season when entering a game as an underdog by +117 or more on the moneyline.The moneyline for this contest implies a 46.1% chance of a victory for Chicago.Against the spreadLast year, the Pistons averaged 115.5 points per game, just 3.9 fewer points than the 119.4 the Bulls allowed.Detroit had a 20-9 record against the spread and a 21-8 record overall last season when putting up more than 119.4 points.When it scored more than 113.6 points last season, Chicago went 38-13-2 against the spread and 35-18 overall.Detroit’s record was 33-15 against the spread and 35-13 overall when it gave up fewer than 117.8 points last season.Last season, the Pistons were the league’s 11th-ranked scoring team (115.5 PPG), while the Bulls were the 28th-ranked defense in terms of points per game (119.4) in NBA action.The sixth-ranked scoring NBA team was Chicago a season ago (117.8 PPG), while the Detroit squad was the 14th-ranked defense (113.6 PPG) in the league.The Pistons totaled 156 more points than their opponents last season (1.9 per game on average), while the Bulls were out-scored by 128 total points (1.6 per game average differential).Over/UnderDetroit had an average implied point total of 116.3 last season, which is 1.7 points lower than its implied total in Wednesday’s game (118).Last year, Detroit scored more than 118 points in a game 37 times.The 121.2-point average implied total last season for Chicago is 5.2 more points than the team’s 116-point implied total in this matchup.How to watch Pistons vs. BullsGame day: Wednesday, October 22, 2025Game time: 8 p.m. ETLocation: Chicago, IllinoisArena: United CenterTV channel: FanDuel Sports Network Detroit – BSDLive stream: Watch this game on Fubo

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