The Cleveland Cavaliers (3-1) are favored (-4.5) to build on a three-game win streak when they visit the Boston Celtics (1-3) at 7 p.m. ET on Wednesday, October 29, 2025 at TD Garden. The matchup airs on ESPN, NBCS-BOS, and FDSOH. The matchup has an over/under of 231.5 points.
Boston won its previous game against the Pelicans, 122-90, on Monday. Anfernee Simons was its leading scorer with 25 points.
Celtics vs. Cavaliers betting information
NBA odds courtesy of BetMGM Sportsbook. Odds updated Tuesday at 9:24 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread: Cleveland -4.5Moneyline: Cleveland -175, Boston +145Total: 231.5 pointsCeltics betting insightsThe Celtics compiled a 39-43-0 ATS record last year.The Celtics were an underdog by 4.5 points or more last season once, and failed to cover the spread.The Celtics and their opponents combined to go over the point total 37 out of 82 times last season.Celtics key playersJayson Tatum: 26.8 PTS, 8.7 REB, 6 AST, 1.1 STL, 45.2 FG%, 34.3 3PT% (250-for-728)Derrick White: 16.4 PTS, 1.1 BLK, 44.2 FG%, 38.4 3PT% (265-for-691)Jaylen Brown: 22.2 PTS, 1.2 STL, 46.3 FG%, 32.4 3PT% (116-for-358)Anfernee Simons: 19.3 PTS, 42.6 FG%, 36.3 3PT% (215-for-593)Payton Pritchard: 14.3 PTS, 47.2 FG%, 40.7 3PT% (255-for-626)Celtics vs. Cavaliers game info