Tyrese Maxey and the Philadelphia 76ers (7-4) are 5.5-point underdogs against Cade Cunningham and the Detroit Pistons (10-2) Friday, November 14, 2025 at Little Caesars Arena. The matchup starts at 7:30 p.m. ET on FDSDET and NBCS-PH. The matchup has an over/under of 232.5 points.

Philadelphia was victorious in its most recent game against the Celtics, 102-100, on Tuesday. Justin Edwards led the way with 22 points, and also had three boards and three assists.

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76ers vs. Pistons betting information

NBA odds courtesy of BetMGM Sportsbook. Odds updated Thursday at 9:24 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread: Detroit -5.5Moneyline: Detroit -225, Philadelphia +185Total: 232.5 points76ers betting insightsThe 76ers are 8-3-0 against the spread this season.The 76ers have a 1-1 record against the spread when an underdog by 5.5 points or more this season.76ers games have gone over the point total in seven out of 11 opportunities (63.6%).76ers key playersTyrese Maxey: 32.1 PTS, 8.3 AST, 1.2 STL, 45.8 FG%, 44.4 3PT% (44-for-99)VJ Edgecombe: 15.4 PTS, 1.4 STL, 40.9 FG%, 36.2 3PT% (21-for-58)Kelly Oubre Jr.: 18 PTS, 50.7 FG%, 35.4 3PT% (23-for-65)Quentin Grimes: 17.3 PTS, 48 FG%, 40.6 3PT% (28-for-69)Andre Drummond: 7.6 PTS, 8.6 REB, 56.6 FG%, 33.3 3PT% (4-for-12)76ers vs. Pistons game info

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