Kelly Oubre Jr. will miss at least two weeks with a left knee injury, the Sixers announced Wednesday night.

Oubre exited the Sixers’ loss last Friday to the Pistons after hyperextending his knee. According to a Sixers official, an MRI on the 29-year-old revealed a left knee LCL sprain and he’ll be re-evaluated in two weeks.

Early in the season, Oubre had been the Sixers’ primary wing player (34.8 minutes per game) and started all of the team’s first 12 games. He averaged 16.8 points and 5.1 rebounds and often handled star assignments defensively.

“He’s done that consistently where he’s got one of better scorers in the league or on the other team, and he just keeps working and working,” Sixers head coach Nick Nurse said after his team’s Nov. 8 win over the Raptors. “He’s been really good.

“He’s done a good job of playing physically and he’s been much better at just being solid — keeping himself in front of his man, challenging shots. They’re going to make some, but he just keeps at it over the course of the game and ends up with a good defensive game.”

Along with Oubre, the Sixers did not have Joel Embiid (right knee injury), Paul George (left knee injury recovery) and Adem Bona (right ankle sprain) on Wednesday night vs. Toronto for the first leg of a back-to-back.

George is expected to be available Thursday against the Bucks. Embiid has been a full participant in the Sixers’ last two practices and was initially listed as doubtful against the Raptors.