From Zxavian Harris to Ty Simpson, here’s one prospect from 12 of the biggest rivalry games this weekend that NFL scouts will be watching closely:

(Note: All games listed in ET.)

FridayNo. 6 Ole Miss at Mississippi State (Noon, ABC)

Ole Miss has a top-50 prospect (or a few of them) almost every year. That isn’t the case in the 2026 class, however, which is ironic considering this could be the most successful season in Rebels history.

Nonetheless, there are a handful of Ole Miss prospects who should hear their names called on Day 3, starting with defensive tackle Zxavian Harris. At 6 feet 7 and 330 pounds with almost 35-inch arms, he is a mammoth lineman who should be a solid NFL rotational player.

Iowa at Nebraska (Noon, CBS)

Iowa has a few future draft picks on its offensive line, but the key prospect to watch will be edge defender Max Llewellyn. At 6-5, 260, the top-100 hopeful is explosive and versatile as a pass rusher, but he tends to be inconsistent as a run defender and tackler. Though his rush skills will be important, his consistency as an edge setter will be even more crucial against Nebraska’s shifty running back, Emmett Johnson, who’s one of only four FBS players with more than 1,200 rushing yards this season.

Max Llewellyn got the sack while only putting one hand on the offensive linemen 😳 pic.twitter.com/Dgt1VJXRC7

— Big Ten Football (@B1Gfootball) September 14, 2025

No. 4 Georgia at No. 23 Georgia Tech (3:30 p.m., ABC)

An ascending NFL prospect, Georgia left tackle Monroe Freeling continues to put impressive play on tape in pass protection. He is balanced in his pass sets, with thudding hands and the recovery skills to stay on his feet and protect the pocket. Freeling only has 15 college starts under his belt and is still developing, especially as a run blocker, but he would upgrade this offensive tackle class if he declares.

No. 3 Texas A&M at No. 16 Texas (7:30 p.m., ABC)

One of the biggest senior risers this season, Texas A&M pass rusher Cashius Howell is fun to watch because of his athletic twitch and play violence. He is undersized, and I want to see him win more consistently aside from using speed to the corner, but he makes his impact felt.

Texas quarterback Arch Manning, who is coming off the best game of his career (six total touchdowns versus Arkansas), has been pressured at an alarming rate this season — he ranks No. 1 in the FBS in times hit while throwing (that is a real stat). How the Longhorns’ offensive line holds up against the Aggies’ front will be key in this heated rivalry.

Arizona at Arizona State (9 p.m., FOX)

After wide receiver Jordyn Tyson missed the previous four weeks with a nagging hamstring injury, it was awesome to see him back on the field for the Sun Devils this past weekend. One of the top offensive prospects eligible for the 2026 NFL Draft, Tyson reminds me of Stefon Diggs with his ability to create space and win at the catch point.

Arizona defensive back Treydan Stukes, a mid-round prospect, lines up primarily inside. But any time he’s matched up with Tyson will be must-see for NFL scouts.

SaturdayNo. 1 Ohio State at No. 15 Michigan (Noon, FOX)

The Buckeyes’ suffocating defense is allowing just 7.6 points per game (no other FBS team is below 11.5), but Michigan’s rushing offense ranks in the top 10 nationally, and it includes dangerous dual-threat quarterback Bryce Underwood. This is the type of matchup in which Ohio State hybrid linebacker Arvell Reese, No. 1 on my updated top 50, will need to be at his best.

With his length and violence, Reese can set the edge and make plays versus the run, while also flashing the burst and closing speed to be disruptive as a pass rusher. Expect to see Reese spying Underwood most of the game, and how that battle plays out will go a long way to determining the outcome.

For Michigan, generating a consistent pass rush from Derrick Moore and Jaishawn Barham, both of whom will be drafted in April, is the recipe for ruining Ohio State’s day.

Clemson at South Carolina (Noon, SEC)

Is this LaNorris Sellers’ final game at South Carolina? This season hasn’t gone according to plan for either the quarterback or his team as a whole, which presents an interesting chicken-or-egg conundrum. Is the supporting cast holding back the quarterback, or is the QB not able to elevate the talent around him? The answer probably lies in between, so Sellers needs to take a step back and make a decision for 2026 that will be best for his long-term development.

In the short-term, Sellers has one last opportunity in 2025 to put impact plays on tape, against a Clemson defense littered with NFL Draft picks — Peter Woods, T.J. Parker, Avieon Terrell, Will Heldt and Wade Woodaz, to name a few.

No. 5 Oregon at Washington (3:30, CBS)

The most influential domino when it comes to NFL Draft decisions is Oregon quarterback Dante Moore. Though scouts think he will return, they also believe how the redshirt sophomore performs in the final games of the season will determine whether or not he goes pro. The Ducks are a touchdown favorite in this matchup, but Washington’s defense ranks in the top 20 and Husky Stadium isn’t an easy place to play.

On one hand, I would love to see Moore return to Eugene and continue developing. History tells us that quarterbacks of his age, with the lack of college starts he currently has, are most likely to fail in the NFL. But I also wouldn’t blame him for striking while the iron is hot and jumping into the 2026 draft pool, where he would be a projected top-five pick and potential No. 1 overall.

No. 12 Vanderbilt at No. 18 Tennessee (3:30, ESPN)

Led by quarterback Diego Pavia and tight end Eli Stowers, Vanderbilt offense’s feels like it has a mismatch against the Tennessee defense. But the Volunteers do have several dudes with NFL futures on defense, including linebacker Arion Carter.

Even at less than 100 percent as he battled through turf toe injuries on both feet, Carter made his presence felt in a win over Florida last weekend. The junior averages 7.7 tackles per game (just behind Georgia’s CJ Allen for the SEC lead), and his reaction speed and instincts jump off the screen. If he declares, Carter would be one of my favorite Day 2 prospects because of his competitive makeup and presence.

Florida State at Florida (4:30, ESPN2)

This rivalry doesn’t have the juice of most years, but that doesn’t mean it’s without interesting prospects to watch.

If your NFL team is in need of an interior lineman who is dominant against the run, Florida State defensive tackle Darrell Jackson Jr. should be high on the wish list. He is stout at the point of attack, making him an immovable object, even against double teams.

And when talking about physically imposing defensive tackles, I’d be remiss not to mention the Gators’ Caleb Banks, who missed almost all of the 2025 season with a foot injury before returning last week against Tennessee. Expect him to be rusty, but scouts are just happy to have any 2025 tape on the first-round hopeful.

North Carolina at NC State (7:30, ACC)

Arguably the top senior tight end in the 2026 draft class, NC State’s Justin Joly should be getting double-digit targets every game. The former 190-pound wide receiver now weighs close to 250, but he still shows similar receiver-like athleticism to work his way open and be a threat after the catch.

TE2 is very much in play for NC State’s Justin Joly in the 2026 NFL Draft.

Last night in win over FSU: 5 targets, 5 catches, 4 1D, game-sealing TD pic.twitter.com/X3gRFdJ4Zz

— Dane Brugler (@dpbrugler) November 22, 2025

No. 10 Alabama at Auburn (7:30, ABC)

Last, but certainly not least, the Iron Bowl. This could be the final game for Auburn defensive end Keldric Faulk, who has the traits to be a top-five pick — anytime we get to see him face off against left tackle Kadyn Proctor will be a treat.

However, the prospect with the most on the line is Alabama quarterback Ty Simpson. Based on the first two months of the season, the redshirt junior was trending toward becoming an early first-round pick. However, some of his inconsistencies have been more persistent on his November tape, shining an even brighter light on his inexperience. How Simpson finishes, both in this game and in the postseason, will go a long way toward determining whether he makes the NFL jump or returns to Tuscaloosa.