Two of the NBA’s best scorers hit the court when Jaylen Brown (fifth, 29.0 PPG) and the Boston Celtics (13-9) host Luka Doncic (first, 35.3 PPG) and the Los Angeles Lakers (16-5) on Friday, December 5, 2025 at 7 p.m. ET on Amazon Prime Video and SportsNet LA. The Celtics are 6.5-point favorites.

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Celtics vs. Lakers Predictions for Friday

Our computer projection model for this contest expects a final result of Celtics 118, Lakers 114.

Moneyline Pick: Celtics (-252)
Total Pick: Over 223.5 (computer predicts 231.3 points)
Pick ATS: Lakers (+6.5)
Recent Celtics vs. Lakers Matchups

Celtics 2025-26 Betting Trends

Boston’s ATS record is 12-10-0 this season.
The Celtics are 4-2 against the spread when favored by 6.5 points or more this season.
Boston’s games have hit the over in 10 out of 21 opportunities (47.6%).
The Celtics have won eight, or 66.7%, of the 12 games they’ve played as favorites this season.
This season, Boston has won four of its six games when favored by at least -252 on the moneyline.
Lakers 2025-26 Betting Trends

So far this year, Los Angeles has compiled a 13-8-0 record against the spread.
When they have played as at least 6.5-point underdogs this season, the Lakers are 2-1 against the spread.
In Los Angeles’ 21 games with a set total, 15 have hit the over (71.4%).
The Lakers have a 7-3 record in games they were the underdog on the moneyline (winning 70% of those games).
Los Angeles has gone 2-1 when playing as a moneyline underdog with odds of +205 or longer (66.7%).

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Celtics vs. Lakers Injury Report

Celtics

Celtics:

Jayson Tatum: Out (Achilles),

Jaylen Brown: Day-To-Day (Illness)

Lakers

Lakers:

Luka Doncic: Day-To-Day (Personal),

Marcus Smart: Day-To-Day (Back)

Celtics vs. Lakers Game Time and TV Channel

Game day: Friday, December 5, 2025
Game time: 7 p.m. ET
TV channel: Amazon Prime Video and SportsNet LA
Location: Boston, Massachusetts
Arena: TD Garden

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