The San Antonio Spurs (15-6) and Cleveland Cavaliers (13-10) meet Friday at Rocket Arena in Cleveland, Ohio. Tip-off is scheduled for 7:30 p.m. ET. Let’s analyze BetMGM Sportsbook’s NBA odds around the Spurs vs. Cavaliers odds and make our expert NBA picks and predictions for the best bets.

2024-25 season series: Cavaliers swept 2-0

Cleveland swept the season series in 2024-25, but it won 124-116 at home on March 27, while San Antonio covered as a 14-point underdog. The Spurs actually covered both meetings, and they’re 5-1 against the spread (ATS) in the past 6 meetings since Dec. 12, 2022, their only outright win in the past 9 in the series.

The Spurs picked up a 114-112 victory Wednesday at the Orlando Magic as 8-point underdogs as the Under (236) cashed, as G De’Aaron Fox went for 31 points on 11-of-20 shooting, while C Luke Kornet posted 5 points and 3 blocks in place of the injury C Victor Wembanyama (calf). San Antonio is 4-1 SU and ATS in the past 5 games, and 7-2 ATS in the past 9 outings. The Over is 3-1 in the past 4 games, too.

The Cavaliers were worked over 122-110 as 10-point favorites against the visiting Portland Trail Blazers Wednesday as the Under (245) cashed. G Donovan Mitchell did his part, as he often does, going for 33 points with 5 assists and 5 rebounds in 34 minutes, while C Evan Mobley posted a double-double with 23 points, 10 rebounds and 5 blocks.

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Spurs at Cavaliers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:32 a.m. ET.

Moneyline (ML): Spurs +145 (bet $100 to win $145) | Cavaliers -180 (bet $180 to win $100)Against the spread: Spurs +4.5 (-115) | Cavaliers -4.5 (-105)Over/Under (O/U): 238.5 (O: -110 | U: -110)Spurs at Cavaliers injuries

Spurs

G Stephon Castle (hip) outC Luke Kornet (ankle) questionableG Jordan McLaughlin (hamstring) outC Victor Wembanyama (calf) out

Cavaliers

C Jarrett Allen (finger) outG Darius Garland (toe) outG Sam Merrill (hand) outF Larry Nance Jr. (calf) outG Tyrese Proctor (personal) outF Max Strus (foot) out

For most recent updates: Official NBA injury report.

Spurs at Cavaliers picks and predictionsPrediction

Cavaliers 115, Spurs 111

PASS.

The Cavaliers (-180) will cost you nearly 2 times your potential return, and that’s just a little too expensive coming off a loss at home against Portland as a double-digit favorite.

The Spurs are without Wemby, but they’ve still posted 4 wins in the past 5 wins, and 7 victories in the previous 9 outings. If anything, San Antonio is worth a roll of the dice.

The SPURS +4.5 (-115) are worth playing lightly, but go with a half-unit play at most.

While the Spurs are without Wemby, and potentially Kornet, the Cavaliers are also missing key parts with Allen and Garland sidelined. San Antonio is 4-1 ATS in the past 5 games, and 7-2 ATS across the last 9 outings, while going 3-1 ATS in the past 4 contests on the road.

The UNDER 238.5 (-110) might be the best play on the board.

San Antonio cashed low last time out in the victory in Orlando, and the Under has a 3-2 advantage in the past 5 road games.

Cleveland hit the Under at a 2-1 pace in the past 3 outings, while going 8-2 across the past 10 contests. The Under is 7-0 in the past 7 games at home, too.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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