The Philadelphia 76ers (13-9) will look to Tyrese Maxey (third in the league scoring 31.6 points per game) when they try to defeat Luka Doncic (first in the NBA with 35.3 PPG) and the Los Angeles Lakers (16-6) on Sunday, December 7, 2025 at Xfinity Mobile Arena. The 76ers are 4.5-point home underdogs in the game, which starts at 7:30 p.m. ET on SportsNet LA and NBCS-PH. The matchup’s over/under is set at 235.5.

On Friday, in its most recent game, Philadelphia defeated the Bucks 116-101. With 22 points, Quentin Grimes was its high scorer.

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76ers vs. Lakers betting information

NBA odds courtesy of BetMGM Sportsbook. Odds updated Sunday at 1:25 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

Spread: Los Angeles -4.5Moneyline: Los Angeles -175, Philadelphia +145Total: 235.5 points76ers betting insightsThe 76ers’ ATS record is 12-10-0 this season.The 76ers are 3-2 against the spread when an underdog by 4.5 points or more this season.The teams have hit the over in 11 of the 76ers’ 22 games with a set total.76ers key playersTyrese Maxey: 31.6 PTS, 7.1 AST, 1.7 STL, 46.7 FG%, 38.2 3PT% (79-for-207)Quentin Grimes: 17 PTS, 45.6 FG%, 38.1 3PT% (51-for-134)VJ Edgecombe: 14.3 PTS, 1.4 STL, 41.5 FG%, 36.7 3PT% (36-for-98)Andre Drummond: 7.5 PTS, 9.2 REB, 55.3 FG%, 39.3 3PT% (11-for-28)Joel Embiid: 18.5 PTS, 1.4 BLK, 44.7 FG%, 25 3PT% (9-for-36)76ers vs. Lakers game info

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