The Los Angeles Lakers (17-6) square off against the San Antonio Spurs (16-7) as 4.5-point favorites on Wednesday, December 10, 2025 at 10 p.m. ET on Amazon Prime Video and SportsNet LA. The matchup has an over/under set at 234.5 points.
Los Angeles was victorious in its most recent game versus the 76ers, 112-108, on Sunday. Luka Doncic was its leading scorer with 31 points.
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Lakers vs. Spurs betting information
NBA odds courtesy of BetMGM Sportsbook. Odds updated Tuesday at 5:26 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread: Los Angeles -4.5Moneyline: Los Angeles -190, San Antonio +154Total: 234.5 pointsLakers betting insightsThe Lakers are 14-9-0 ATS this season.The Lakers are 5-5 against the spread when favored by 4.5 points or more this season.The teams have hit the over in 16 of the Lakers’ 23 games with a set total.Lakers key playersLuka Dončić: 35 PTS, 9.2 REB, 9.1 AST, 1.5 STL, 47.2 FG%, 33.5 3PT% (61-for-182)Austin Reaves: 28.4 PTS, 6.7 AST, 1.1 STL, 50.9 FG%, 37 3PT% (57-for-154)Deandre Ayton: 15.3 PTS, 8.8 REB, 1.1 BLK, 70.6 FG%Rui Hachimura: 14 PTS, 53.6 FG%, 46.2 3PT% (43-for-93)Jake Laravia: 8.9 PTS, 1.2 STL, 46.3 FG%, 33.3 3PT% (23-for-69)Lakers vs. Spurs game infoGame day: Wednesday, December 10, 2025Game time: 10 p.m. ETLocation: Los Angeles, CaliforniaArena: Crypto.com ArenaTV channel: Amazon Prime Video, SportsNet LALive stream: Watch this game on Prime Video
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