The Portland Trail Blazers (12-16) are 5.5-point underdogs as they attempt to continue a three-game win streak when they host the Detroit Pistons (22-6) on Monday, December 22, 2025 at Moda Center. The contest airs at 10 p.m. ET on KUNP and FDSDET.

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Listen to the game on Rip City Radio 620 Portland

Pistons vs. Trail Blazers Predictions for Monday

Our computer projections model for this contest predicts a final result of Pistons 119, Trail Blazers 116.

Moneyline Pick: Pistons (-230)
Total Pick: Over 234.5 (computer predicts 235.2 points)
Pick ATS: Trail Blazers (+5.5)
Recent Pistons vs. Trail Blazers Matchups

Pistons 2025-26 Betting Trends

Detroit is 16-12-0 ATS this season.
The Pistons are 7-6 against the spread when favored by 5.5 points or more this season.
Detroit has hit the over in 14 of its 28 games with a set total (50%).
The Pistons have been favorites in 22 games this season and won 17 (77.3%) of those contests.
Detroit has been at least a -230 moneyline favorite 12 times this season and won all of those games.
Trail Blazers 2025-26 Betting Trends

So far this season, Portland has put together a 15-13-0 record against the spread.
The Trail Blazers have a 7-2 record against the spread this season when an underdog by 5.5 points or more.
A total of 18 of Portland’s 28 games with a set total have hit the over (64.3%).
The Trail Blazers have won seven of the 17 games they were the underdog on the moneyline this season (41.2%).
In games it has played as a moneyline underdog with odds of +190 or longer, Portland has gone 2-5 (28.6%).

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Pistons vs. Trail Blazers Injury Report

Pistons

Pistons: None

Trail Blazers

Trail Blazers:

Damian Lillard: Out For Season (Achilles),

Scoot Henderson: Out (Hamstring),

Blake Wesley: Out (Foot),

Matisse Thybulle: Out (Thumb),

Jrue Holiday: Day-To-Day (Calf),

Jerami Grant: Day-To-Day (Achilles)

Pistons vs. Trail Blazers Game Time and TV Channel

Game day: Monday, December 22, 2025
Game time: 10 p.m. ET
TV channel: KUNP and FDSDET
Location: Portland, Oregon
Arena: Moda Center
Live stream: Watch this game on Fubo (Regional restrictions may apply)

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