Jan. 21, 2026, 10:47 a.m. ET

The Detroit Pistons (31-10) and New Orleans Pelicans (10-35) meet Wednesday. Tip-off from Smoothie King Center in New Orleans, Louisiana, is set for 8 p.m. ET. Let’s analyze BetMGM Sportsbook’s NBA odds around the Pistons vs. Pelicans odds and make our expert NBA picks and predictions for the best bets.

2024-25 season series: Pistons swept 2-0

The Pistons barely edged the Boston Celtics 104-103 Monday, failing to cover as a 2.5-point home favorite with the Under (223.5) cashing. Detroit was led by F Tobias Harris, who scored 25 points on 11-for-20 shooting. It has won 3 straight games and 6 of its last 7, going 4-3 against the spread (ATS) in that span. The Pistons are 22-19 ATS on the season.

The Pelicans lost to the Houston Rockets 119-110 Sunday, covering as a 13.5-point road underdog. The Under (232.5) hit. G Trey Murphy III tallied 21 points on 7-for-15 shooting. New Orleans has lost 4 of its last 5 games, but its offense has been surging, scoring at least 116 points in 5 of its last 6 contests. It is 23-21-1 ATS on the season.

Watch the NBA on Fubo!Pistons at Pelicans odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:47 a.m. ET.

Moneyline (ML): Pistons -425 (bet $425 to win $100) | Pelicans +320 (bet $100 to win $320)Against the spread (ATS): Pistons -9.5 (-110) | Pelicans +9.5 (-110)Over/Under (O/U): 233.5 (O: -110 | U: -110)Pistons at Pelicans key injuries

Pistons

G Caris LeVert (illness) out

Pelicans

G Jose Alvarado (oblique) outF Herbert Jones (ankle) questionableG Dejounte Murray (Achilles) outF Zion Williamson (illness) questionable

For most recent updates: Official NBA injury report.

Pistons at Pelicans picks and predictionsPrediction

Pistons 118, Pelicans 111

PASS.

Avoid this play. The Pistons (-425) should win with ease, but they are far too expensive to consider to win outright. They’re not nearly worth 4 times your money.

BET PELICANS +9.5 (-110).

The Pelicans’ offensive surge is worth noting here. They have scored at least 110 points in 6 straight games, and while they have a porous defense, that consistency should keep this one close. They are 3-3 ATS in their last 6 games.

The Pistons are 3-7 ATS in their last 10 games as a favorite. Detroit has also been on a 6-game homestand and is 2-4 ATS in its last 6 contests. Take PELICANS +9.5 (-110).

BET UNDER 233.5 (-110).

The Pistons have gone Under in 10 straight games, and their lack of offensive firepower has been mainly why. They have scored 108 points or fewer in 4 of their last 5 games.

New Orleans has gone Under in 7 of its last 10 games. It has been a bit better defensively, too, allowing 117 points or fewer in 4 of its last 8 contests.

Take UNDER 233.5 (-110).

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