The New York Knicks and Philadelphia 76ers are scheduled to meet in a key NBA matchup at Xfinity Mobile Arena on Wednesday, February 11, 2026, starting at 7:30 PM ET.

With a new batch of NBA odds boosts now live on Bet365—headlined by the “Knicks World Tour” parlay—the analysts at Dimers conducted 10,000 new 76ers-Knicks simulations that included box score projections for both teams. The results were compared to current NBA odds to curate the Knicks-76ers preview below.

Knicks vs. 76ers betting preview

Led by the likes of Jalen Brunson, Karl-Anthony Towns, and Mikal Bridges, the Knicks are up against a 76ers lineup that includes Joel Embiid, Tyrese Maxey, and Kelly Oubre. While Philadelphia sits sixth in the Eastern Conference, they continue to navigate the absence of the suspended Paul George.

Explore the latest spread, total, and moneyline odds and probabilities for the Knicks-76ers game at Xfinity Mobile Arena below.

Game detailsTeams: New York Knicks vs. Philadelphia 76ersDate: Wednesday, February 11, 2026Time: 7:30 p.m. ESTLocation: Xfinity Mobile ArenaNBA Standings: Current NBA StandingsNBA News: Latest updates from NBA.comOddsSpread: Knicks +2.5 (-114), 76ers -2.5 (-105)Moneyline: Knicks +115, 76ers -132Total: Over/Under 225.5 (-105/-115)Bet365 Boosted Special: Knicks World Tour

Combine a New York road victory with these two high-impact player milestones for an enhanced payout.

Money Line: NY KnicksJalen Brunson: 30+ PointsKarl-Anthony Towns: 10+ Rebounds

Payout Breakdown:

Previous Odds: +470Boosted Odds: +550Potential Return: A $10 wager returns $65.Expert prediction: Knicks vs. 76ers

Leveraging state-of-the-art data analysis, the experts at Dimers have performed 10,000 simulations of Wednesday’s game. According to the predictive model, the 76ers are more likely to defeat the Knicks at Xfinity Mobile Arena with a 60% chance of winning.

Elsewhere on the betting board, Dimers predicts that the 76ers (-2.5) have a 51% chance of covering the spread, while the over/under total of 225.5 points has a 51% chance of going over.

Best bet

Our top pick for the Knicks vs. 76ers game on Wednesday is to bet on the 76ers moneyline (-132). This expert advice is formulated through detailed simulations and valuable wagering intelligence.

Score prediction

Dimers’ predicted final score for the New York vs. Philadelphia game has the 76ers winning 114-111. This prediction is based on each team’s average score following 10,000 game simulations.

Knicks vs. 76ers prop picks and boxscore projections

To further analyze the potential impact of individual players, here is a breakdown of the projected box scores for both teams:

New York Knicks prediction

Jalen Brunson: 27 PTS, 3 REB, 6 ASTKarl-Anthony Towns: 19 PTS, 11 REB, 3 ASTMikal Bridges: 16 PTS, 4 REB, 4 ASTLandry Shamet: 12 PTS, 2 REB, 2 ASTJosh Hart: 12 PTS, 8 REB, 6 AST

Philadelphia 76ers prediction

Joel Embiid: 26 PTS, 8 REB, 4 ASTTyrese Maxey: 26 PTS, 4 REB, 7 ASTKelly Oubre: 17 PTS, 6 REB, 2 ASTVJ Edgecombe: 14 PTS, 6 REB, 4 ASTQuentin Grimes: 11 PTS, 4 REB, 4 ASTNBA Wednesday: Knicks vs. 76ers

Get ready for Wednesday’s action at Xfinity Mobile Arena, starting at 7:30 p.m. EST. We emphasize that all of the NBA predictions and best bets on this page are based on 10,000 data-driven simulations and are accurate at the time of publication.

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