The Memphis Grizzlies (21-33) are heavy underdogs (+10.5) as they attempt to stop a four-game road losing streak when they square off against the Miami Heat (30-27) on Saturday, February 21, 2026 at Kaseya Center. The game airs at 8 p.m. ET on FDSSUN, FDSSE, and WPLG.

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Heat vs. Grizzlies Predictions for Saturday

Our computer projection model for this encounter expects a final score of Heat 121, Grizzlies 113.

Moneyline Pick: Heat (-442)
Total Pick: Under 238.5 (computer predicts 234.7 points)
Pick ATS: Grizzlies (+10.5)
Recent Heat vs. Grizzlies Matchups

Heat 2025-26 Betting Trends

Miami is 33-23-1 against the spread this season.
In games they have played as at least 10.5-point favorites this season, the Heat are 2-1 against the spread.
Miami’s games have hit the over in 28 out of 54 opportunities (51.9%).
This season, the Heat have been favored 28 times and won 17, or 60.7%, of those games.
Miami has played as a favorite of -442 or more twice this season and won both games.
Grizzlies 2025-26 Betting Trends

Memphis has a 25-29-0 record against the spread this year.
The Grizzlies have a 3-3 record against the spread when an underdog by 10.5 points or more this year.
Of Memphis’ 54 games with a set total, 25 have hit the over (46.3%).
The Grizzlies have won nine of the 36 games they were the underdog on the moneyline this season (25%).
Memphis has not yet won a game when entering as a moneyline underdog with odds of +342 or longer in six chances.

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Heat vs. Grizzlies Injury Report

Heat

Heat: None

Grizzlies

Grizzlies:

Ja Morant: Out (Elbow),

Kentavious Caldwell-Pope: Out For Season (Finger),

Zach Edey: Out (Ankle),

Brandon Clarke: Out (Calf),

Walter Clayton: Day-To-Day (Calf),

Scotty Pippen Jr.: Day-To-Day (Toe),

Ty Jerome: Day-To-Day (Calf),

Cedric Coward: Day-To-Day (Knee),

Santi Aldama: Day-To-Day (Knee)

Heat vs. Grizzlies Game Time and TV Channel

Game day: Saturday, February 21, 2026
Game time: 8 p.m. ET
TV channel: FDSSUN, FDSSE, and WPLG
Location: Miami, Florida
Arena: Kaseya Center

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