March 20, 2026, 11:18 a.m. ET

The Portland Trail Blazers (34-36) visit the Minnesota Timberwolves (43-27) Friday night for an 8 p.m. ET tip from Target Center in Minneapolis, Minnesota. Let’s analyze NBA odds around the Trail Blazers vs. Timberwolves odds and make our expert NBA picks and predictions for the best bets.

Season series: Timberwolves lead 3-0

Portland has won back-to-back games after taking down the Indiana Pacers 127-119 on Wednesday, though the Blazers failed to cover as 12.5-point road favorites with the Over (232.5) hitting. F Deni Avdija scored a game-high 32 points with 11 rebounds, while C Donovan Clingan (28, 13) also added a double-double in the victory.

Minnesota has won back-to-back games after blowing out the Utah Jazz 147-111 on Wednesday, covering as a 13.5-point home favorite with the Over (231.5) hitting with ease. G Ayo Dosunmu scored a team-high 23 points while C Rudy Gobert and F Julius Randle each added 21 in the dominant showing.

The Timberwolves took down the Trail Blazers 124-121 with the Blazers covering as 6.5-point home underdogs and the Over (234.5) hitting in their most recent matchup on Feb. 24. In the three games this season, the Timberwolves are 3-0 straight up (SU) but the Blazers are 2-1 against the spread (ATS). The Over has hit in all three games.

Watch the NBA on Fubo!Trail Blazers at Timberwolves odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 11:10 a.m. ET.

Moneyline (ML): Trail Blazers +115 (bet $100 to win $115) | Timberwolves -140 (bet $140 to win $100)Against the spread (ATS): Trail Blazers +2.5 (-110) | Timberwolves -2.5 (-110)Over/Under (O/U): 231.5 (O: -110 | U: -110)Trail Blazers at Timberwolves key injuries

Trail Blazers

G Vit Krejci (calf) questionableG Damian Lillard (Achilles) outG Shaedon Sharpe (leg) out

Timberwolves

G Anthony Edwards (knee) outC Naz Reid (ankle) questionable

For most recent updates: Official NBA injury report.

Trail Blazers at Timberwolves picks and predictionsPrediction

Timberwolves 116, Trail Blazers 111

PASS.

There is better value on the Timberwolves (-140) to cover the spread in this matchup.

BET TIMBERWOLVES -2.5 (-110).

The Wolves have won each of the three meetings between these teams this season, all of which came by at least 3 points. They have covered in 3 of their last 4 games, including each of their last 3 as favorites and in back-to-back games at home. All but 1 (42 of 43) of their wins this season have come by at least 3 points, including each of their last 17, nearly guaranteeing a cover with a victory.

The Blazers are 3-7 ATS over their last 10 games and have failed to cover in 3 of their last 4. They are 1-6 ATS in their last 7 games on the road and 1-3 ATS in their last 4 as underdogs.

BET UNDER 231.5 (-110).

The Blazers have scored 114 or fewer points in 2 of their last 3 and in 6 of their last 10. They have hit the Under in 2 of their last 3 and have allowed 111 or fewer points in 5 of their last 7.

The Wolves have scored 116 or fewer points in 2 of their last 3 and in 4 of their last 7. They have allowed 111 or fewer points in back-to-back games.

In a meeting that does not feature Edwards, the Wolves’ scoring capabilities will be more limited, leading to fewer opportunities and fewer scoring, giving good value to the Under.

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