March 22, 2026, 12:32 a.m. ET

The Portland Trail Blazers (35-36) and Denver Nuggets (43-28) meet Sunday at Ball Arena in Denver, Colorado. Tip-off is 5 p.m. ET (NBATV). Let’s analyze NBA odds around the Trail Blazers vs. Nuggets odds and make our expert NBA picks and predictions for the best bets.

Season series: Tied 1-1 with split in Portland — Denver winning 109-107 Oct. 31 and Portland winning 157-103 Feb. 20

The Trail Blazers beat the Minnesota Timberwolves 108-104 Friday, covering as a 1-point road underdog with the Under (231.5) cashing. Portland has ripped off 3 straight wins and is 2-1 against the spread (ATS) in those. It is 37-34 ATS on the season.

The Nuggets edged the Toronto Raptors 121-115 Friday, but failed to cover as a 7-point home favorite as the Under (238.5) hit. Denver has traded off winning and losing over its last 5 games and is 2-3 ATS across its last 5 outings. It is 39-32 ATS.

Watch the NBA on Fubo!Trail Blazers at Nuggets odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:22 a.m. ET.

Moneyline (ML): Trail Blazers +290 (bet $100 to win $290) | Nuggets -360 (bet $360 to win $100)Against the spread (ATS): Trail Blazers +9 (-106) | Nuggets -9 (-114)Over/Under (O/U): 242.5 (O: -108 | U: -112)Trail Blazers at Nuggets key injuries

Trail Blazers

F Jerami Grant (foot) questionableG Damian Lillard (Achilles) outG Shaedon Sharpe (fibula) out

Nuggets

F Peyton Watson (hamstring) questionable

For most recent updates: Official NBA injury report.

Trail Blazers at Nuggets picks and predictionsPrediction

Nuggets 122, Trail Blazers 115

PASS.

Avoid this play. The Nuggets (-360) should win outright, but aren’t worth even close to more than 3 1/2 times your money here.

BET TRAIL BLAZERS +9 (-106).

The Nuggets’ defense has had some major flaws over the last week. They’ve given up at least 115 points in 3 of their last 4 games and are 1-3 ATS in those contests.

For Portland, it has gone 2-0 ATS in its last 2 games as an underdog. On top of that, it is 2-1 ATS in its last 3 contests and has scored at least 114 points in 2 of those. Expect it to score enough to keep things close.

BET UNDER 242.5 (-112).

This total is just too lofty to consider.

The Trail Blazers have gone 1-3 O/U in their previous 4 outings, having allowed 109 points or fewer in 3 of those games. The Nuggets have gone south of the total in 3 straight games. Denver ranks 20th in pace, so the tempo of this game should be slower as well.

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