Five takeaways from the Miami Heat’s 149-128 loss to the Cleveland Cavaliers (46-28) on Friday night at Rocket Arena to fall to 1-1 on its three-game trip. The Heat (39-35) will close the trip against the Pacers in Indianapolis on Sunday:

The Heat earned a 17-point win in Cleveland on Wednesday. But Friday’s matchup brought back memories from last season’s first-round playoff series between the two teams that ended in historic humilation for the Heat.

The Cavaliers outscored the Heat by a total of 122 points in the four-game sweep in the first round of last season’s playoffs for the most lopsided playoff series in NBA history.

The Cavaliers won Friday’s matchup by 21 points and scored 149 points. It’s the most points that the Heat has allowed in a game in franchise history and it’s also tied for the second-most points that the Cavaliers have scored in a game in franchise history.

“It’s extremely disappointing,” Heat coach Erik Spoelstra said of Friday’s defensive effort. “We’ve put in the time. The guys have put in blood, sweat and tears to develop a top-four defense two weeks ago. And when we need it the most is when we’ve let it disappear.”

Cleveland led from start to finish, ending the first quarter with a 13-point lead and then outscoring the Heat 41-19 in the second quarter before entering halftime with a huge 81-46 advantage.

The Cavaliers led by as many as 36 points, but the Heat went on a third-quarter run to cut the deficit to 19 in the final seconds of the period. But guard Keon Ellis hit a 32-footer at the third-quarter buzzer to push the Cavaliers into the fourth quarter with a 22-point lead.

The Cavaliers continued to pour it on in the fourth quarter, beginning the period on an 8-2 run to extend its lead up to 28 points and put the Heat away.

The Heat waved the white flag midway through the fourth quarter, emptying its bench.

“What we needed to have was a great disposition to start the game versus a team that was very motivated and on top of their game,” Spoelstra continued. “So maybe they get off to a good start, but your defense can weather the storm and it ends up being a six to eight-point lead instead of a 20-plus point lead.”

The Heat limited a potent Cavaliers offense to 103 points on 43.2 percent shooting from the field and 12 of 37 (32.4 percent) shooting on threes in Wednesday’s win. Miami actually held Cleveland to its worst offensive rating in more than two weeks on Wednesday.

But the Cavaliers, which entered with the NBA’s sixth-best offensive rating this season, shredded the Heat’s defense on Friday. Cleveland exploded for a season-high 149 points on 53.6 percent shooting from the field and 19-of-41 (46.3 percent) shooting from three-point range.

The Cavaliers ended up outscoring the Heat 57-45 from three-point range and 52-46 in the paint on Friday. The Heat finished with its second-worst single-game defensive rating of the season, allowing the Cavaliers to score at a rate of 136.7 points per 100 possessions.

The Heat, which has had a top-five defensive rating in the NBA for most of the season, has trended in the wrong direction in that area recently. Over its current 1-6 stretch, the Heat has posted the league’s fourth-worst defensive rating.

The Cavaliers did this despite a quiet game from star guard Donovan Mitchell, who closed with just six points on 1-of-10 shooting from the field and 0-of-3 shooting on threes.

Cavaliers center Jarrett Allen made a big impact in his return from a 10-game absence stemming from a knee injury, finishing his first game in weeks with 18 points, 10 rebounds and one block in 18 minutes.

Cavaliers forward Evan Mobley added 23 points, 10 rebounds and three assists.

Cavaliers guard James Harden recorded 17 points and 14 assists.

For the Heat, Jaime Jaquez Jr. scored a team-high 20 points on 9-of-13 shooting from the field and 2-of-5 shooting on threes.

“We’ve got to come out with better energy, better focus, a better disposition on the defensive end,” Heat guard Tyler Herro said of what needs to be better moving forward. “Not too sure how [Friday’s loss] happened, but it happened.”

The Heat used its new preferred starting lineup for the second straight game, but it didn’t go well.

After using the starting unit of Davion Mitchell, Herro, Norman Powell, Andrew Wiggins and Bam Adebayo for the first time since Jan. 13 in Wednesday’s win over the Cavaliers, the Heat again went with that starting lineup on Friday.

But after this starting group outscored the Cavaliers by three points in 14 minutes together on Wednesday, the Heat’s starters finished as a negative on Friday.

The Heat’s starting lineup was outscored by six points in 14 minutes together on Friday.

The Heat’s starters were outscored 21-10 to begin the game before Spoelstra turned to the bench for the first time on Friday.

The Heat starters were outscored by a total of 14 points in seven first-half minutes.

The Heat starting unit’s only positive minutes on Friday came to begin the third quarter when the Cavaliers were already ahead by more than 30 points. Miami’s starters outscored Cleveland by eight points during the first 6:44 of the second half.

“We need to just keep figuring it out,” Adebayo said when asked about the Heat’s new starting unit. “Everybody keep buying in and we’ll see where it gets us.”

It was a rough night for the Heat’s three starting guards, as Herro, Mitchell and Powell combined for just 28 points on 10-of-29 (34.5 percent) shooting from the field and 3-of-13 (23.1 percent) shooting from three-point range.

Herro finished with 11 points on 4-of-13 shooting from the field and 1-of-4 shooting on threes, three rebounds and five assists.

Mitchell recorded two points on 1-of-6 shooting from the field and 0-of-4 shooting on threes, four rebounds and four assists.

Powell contributed 15 points on 5-of-10 shooting from the field and 2-of-5 shooting on threes, three rebounds and two assists.

Regardless of the results, it seems like Spoelstra will stick with this starting group for the final few weeks of the regular season after going through 25 different starting lineups so far this season.

The Heat extended its bench rotation on Friday, as it searched for answers amid its blowout loss. But the best reserve on Friday was a familiar face on the Cavaliers’ roster.

The Heat started with the same bench rotation that it went with on Wednesday, using Pelle Larsson, Jaquez, Kel’el Ware and Kasparas Jakucionis as its first four reserves on Friday.

But the Heat then subbed in three-point shooting forward Simone Fontecchio as its 10th man. Fontecchio entered for his first action of the night with 8:36 left in the second quarter and the Heat already in a 16-point hole.

Jaquez scored a team-high 20 points off the Heat’s bench.

Ware added 14 points and eight rebounds off the bench.

But the reserve of the night was ex-Heat forward Max Strus, who is now in his third season with the Cavaliers.

Strus sat out Wednesday’s matchup between the two teams because it was on the second night of a back-to-back for the Cavaliers, and he just recently returned from a serious foot injury. But Strus made his presence known on Friday, totaling a game-high 29 points on 10-of-14 shooting from the field and 8-of-11 shooting from three-point range in just his fifth game of the season.

It marked the most points that Strus has scored in a game since joining the Cavs.

Strus was hot from the start, scoring 12 points on 4-of-5 shooting from three-point range while playing 5:19 in Friday’s first quarter. Strus went on to enter halftime with a game-high 22 points.

“He’s ignitable,” Spoelstra said of his former player. “And he’s probably ornery when he has to sit out a game. So that’s usually when he’s most locked in. I kind of wish he would have played the other night. But yeah, that’s certainly what he’s capable of.”

The only unavailable Heat players were the three-way contract trio of Vlad Goldin, Trevor Keels and Jahmir Young, who are all in the G League. Also, Terry Rozier remains away from the team following his October arrest.

With Thursday’s loss, the Heat fell to 4-4 in the eight games that it has had its full standard roster available for this season (not including Rozier).

Adebayo has been playing his best basketball of the season in recent weeks, but he has hit a bit of a shooting slump.

Adebayo closed Friday’s loss with 14 points on 3-of-14 shooting from the field and 1-of-8 shooting on threes, 16 rebounds, three assists, one steal and one block in 30 minutes.

Over the last three games, Adebayo has averaged 16.3 points per game on 14-of-50 (28 percent) shooting from the field and 4-of-27 (14.8 percent) shooting from three-point range.

While it has been a strong season for Adebayo, it has also been an inefficient shooting season for him. Adebayo is shooting a career-low 43.9 percent from the field this season.

The Heat fell deeper into play-in tournament territory.

The Heat already entered Friday at the bottom of the play-in tournament as the Eastern Conference’s 10th-place team. And Friday’s loss pushed the Heat even further away from climbing out of the play-in tournament.

The No. 10 Heat (39-35) is now one loss behind the No. 9 Orlando Magic (39-34) and No. 8 Charlotte Hornets (39-34).

The Heat is also two losses behind the No. 7 Philadelphia 76ers (40-33) and No. 6 Atlanta Hawks (41-33). The Heat is three losses behind the No. 5 Toronto Raptors (41-32).

The NBA’s play-in tournament features the seventh-through-10th-place teams competing for the final two playoff seeds in each conference.

The Heat, which has needed to qualify for the playoffs through the NBA’s play-in tournament in each of the last three seasons, needs to finish among the East’s top six teams to clinch a playoff spot and avoid the play-in tournament.

The Heat has just eight regular-season games left to play.