The Los Angeles Clippers (39-36) and Portland Trail Blazers (38-38) are battling for seeding in the play-in tournament in the Western Conference with just two weeks to go in the regular season.

The Clippers and Trail Blazers have met twice this season, with Los Angeles winning both meetings. Tip-off for Tuesday’s head-to-head matchup is scheduled for 11:00 p.m. ET on NBC and Peacock, with the Clippers being listed as 6.5-point favorites.

Below, we’ll break down our Trail Blazers vs. Clippers prediction and picks for Tuesday night’s game. Make your NBA picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!

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Trail Blazers vs. Clippers Prediction, Spread, Over/Under

The Clippers have been on fire lately, winning five consecutive games coming into Tuesday’s contest. Los Angeles currently sits in eighth place in the Western Conference playoff race and is primed for a play-in spot.

Despite selling players like PG James Harden and C Ivica Zubac at the NBA trade deadline, the Clippers’ young assets have paid huge dividends. PG Darius Garland is averaging 22.1 points and 7.4 assists, while SF-SG Bennedict Mathurin has proven to be a huge scoring threat on the wing.

The Trail Blazers also find themselves battling for seeding in the play-in after clinching a postseason berth. Portland is in ninth place, just 1.5 games behind Los Angeles, making Tuesday’s contest critical.

Trail Blazers SF Deni Avdija finally appears to be healthy after dealing with a back injury that had sidelined him. Avdija’s averaged 21.3 points and 6.4 rebounds while shooting 43.9% from the field in March.

Trail Blazers vs. Clippers Spread, Over/Under

The Clippers are 6.5-point home favorites, returning a 1.42x payout on PrizePicks Team Picks if they win outright.

The Trail Blazers are road underdogs and return a 2.85x payout if they win outright, per PrizePicks Team Picks, where you can earn money with your picks in 35 states.

Spread: Los Angeles Clippers -6.5Over/Under: 227.5Game Winner Payout: Trail Blazers 2.85x | Clippers 1.42x

Team Picks data is live as of writing and is subject to change.

Trail Blazers vs. Clippers Injury Report

Let’s dive into the full Trail Blazers vs. Clippers injury report for Tuesday, via NBA.com.

Portland Trail Blazers Injury ReportPF Jerami Grant (calf): OUTG Vit Krejci (calf): OUTLos Angeles Clippers Injury ReportC Isaiah Jackson (ankle): OUTTrail Blazers vs. Clippers Prediction on Spread – 3/31/26

Here are the key stats to know before locking in your Trail Blazers vs. Clippers prediction against the spread for Tuesday, March 31, on PrizePicks.

The Clippers have a 12-13 against-the-spread record as a home favorite, producing a 48.0% cover rate.The Trail Blazers are 4-2 ATS in their last six games.Los Angeles is one of the most efficient shooting teams in the NBA, connecting on 48.6% of its shots (third in the league).Portland shoots 34.0% from beyond the arc, ranking dead last.The Clippers have averaged 125.4 PPG during their current five-game winning streak, a significant increase from their 114.0 PPG season average.The Clippers are 3-1 ATS in the last four meetings vs. the Trail Blazers and have won all four of those matchups outright.Trail Blazers vs. Clippers Picks for PrizePicks Today: 3/31/26

Here are two of the top Trail Blazers vs. Clippers picks to consider for Tuesday, March 31. Today’s PrizePicks NBA player picks feature Clippers PG Darius Garland and Trail Blazers SF Deni Avdija.

Clippers PG Darius Garland vs. Trail Blazers Projection: 26.5 Pts + AstsGarland has averaged a combined 30.7 points and assists over his last 10 games.The Clippers’ newcomer PG has registered at least 27 points and assists in seven of those 10 contests.Garland is shooting 54.2% (45-of-83) from 3-point land across his last 10 contests.DG has scored 20+ points in seven of those outings, including two 30-point performances.

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Trail Blazers SF Deni Avdija vs. Clippers Projection: 32.5 Pts + RebsAvdija has averaged a combined 28.4 points and rebounds across his last 10 contests.The Trail Blazers’ star SF has recorded at least 33 points and rebounds in just two of his last 10 games.Avdija is shooting 20.0% (10-of-50) from deep during that span.According to NBA Advanced Stats, Avdija has pulled down only 24.1% of his contested rebound opportunities this season.Make Trail Blazers vs. Clippers Picks on PrizePicks

The Clippers and Trail Blazers seem bound for the play-in tournament when the NBA postseason begins next month. Entering Tuesday, the two teams are separated by only 1.5 games in the standings, making this a pivotal bout.

You can make Trail Blazers vs. Clippers picks on PrizePicks and PrizePicks Team Picks to earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 35 states.

Stick around with the Playbook for continued NBA predictions, picks, and news.

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