May 11, 2026, 10:28 p.m. ET
The Minnesota Timberwolves and San Antonio Spurs meet Tuesday in Game 5 of their second-round Western Conference playoff series. Tip from Frost Bank Center in San Antonio, Texas, is set for 8 p.m. ET (NBC / Peacock). Let’s analyze NBA odds around the Timberwolves vs. Spurs odds and make our expert NBA picks and predictions for the best bets.
Playoff series: Tied 2-2
The Timberwolves beat the Spurs 114-109 Sunday, covering as a 5.5-point home underdog with the Over (218.5) cashing. C Victor Wembanyama, the Spurs’ leading scorer and main defensive weapon, was ejected after playing just 12 minutes for a flagrant foul on F Naz Reid. Minnesota was led by G Anthony Edwards, who scored 16 of his game-high 36 points in the fourth quarter. He hit 13 of 22 shots.
San Antonio finished with 62 wins in the regular season, the second-best record in the NBA. It beat the Portland Trail Blazers in 5 games in the first round and has won Game 2 and Game 3 against the Timberwolves.
The Wolves downed the Denver Nuggets in 6 games in the first round, going 1-2 straight up and against the spread (ATS) on the road. They finished the regular season 48-33 straight up and 36-45 ATS.
Watch the NBA on Fubo!Timberwolves at Spurs odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 10:17 p.m. ET.
Moneyline (ML): Timberwolves +320 (bet $100 to win $320) | Spurs -425 (bet $425 to win $100)Against the spread (ATS): Timberwolves +10.5 (-115) | Spurs -10.5 (-105)Over/Under (O/U): 218.5 (O: -110 | U: -110)Timberwolves at Spurs key injuries
Timberwolves
G Donte DiVincenzo (achilles) out
Spurs
G De’Aaron Fox (ankle) questionable
For most recent updates: Official NBA injury report.
Timberwolves at Spurs picks and predictionsPrediction
Spurs 117, Timberwolves 104
PASS.
Avoid this play. The Spurs (-425) should win at home after the Wolves (+320) evened the series in Game 4, but San Antonio is far too expensive to consider here.
BET SPURS -10.5 (-105).
The Spurs have had the edge at home, while the Wolves have struggled on the road in the playoffs. San Antonio is 3-2 ATS in its 5 home games and has covered in each win. It has scored at least 114 points in 5 of its last 7 games, so the Spurs should put up enough to cover in this one.
The Timberwolves are 2-3 ATS on the road in the playoffs and have had offensive woes against an aggressive San Antonio defense. They have scored 108 points or fewer in all but 1 game in the series. Minnesota was just 15-17 ATS as an underdog during the regular season. It should struggle on the road after exceeding expectations in Game 4.
BET OVER 218.5 (-110).
With Wembanyama avoiding a suspension, he should be back and ready to dominate. The Spurs still put up 109 points without him for most of Game 4, so they have a deep arsenal of weapons. San Antonio has scored at least 115 points in 2 of its last 3 games, going Over in each of those.
The Timberwolves’ defense held the Nuggets to sub-100 points in 3 of 6 opening-round games, but they have had real issues with the Spurs. Minnesota has scored 111 points per game in the last 2 contests, while allowing at least 115 points per game.
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