Detroit Pistons vs Philadelphia 76ers Predictions
Best Bet
Under 226.5 Points @ -105
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We Think Under 226.5 is the Value Bet
The Unders looks the way to go when the Pistons meet the Sixers. The line looks too high at 226.5 and odds of -105 could favor bettors who go below that total.
Get our preferred Pistons vs Sixers picks, highlighting our Best Bet, Player Props, Same Game Parlay and Correct Score Prediction. Dive into each section below for the complete analysis and reasoning behind the plays.
Detroit Pistons vs Philadelphia 76ers Preview
The Detroit Pistons hit the hardwood against the Philadelphia 76ers in this NBA contest.
Detroit Pistons have won back-to-back games. A 128-111 triumph recently occurred on the road at Kaseya Center when playing Miami Heat. John Collins dropped 23 points, as Paul Reed finished with 19 and Duncan Robinson 17.
Philadelphia 76ers last game was a 127-116 home win. This victory over Milwaukee Bucks at Xfinity Mobile Arena was their third successive victory. Joel Embiid delivered an outstanding performance when registering a triple-double that consisted of 28 points, 11 rebounds and 10 assists.
H2H: Pistons 116-93 Winners in Most Recent H2H
The Pistons triumphed 116-93 when they last played the Sixers. This head-to-head was played at Xfinity Mobile Arena. It’s been five victories on the bounce for the Pistons when playing the Sixers. On the head-to-head front, they have won 6 of the past 10.
Pistons
2
0
1
124.5
112
12.5
1-0
1-0
0-0
2-0
2-0
2W
76ers
3
0
1
115.7
107.3
8.4
2-0
1-0
1-0
3-0
3-0
3W
Detroit Pistons – Last 10 Games
6 wins and 4 losses in the past 10 games. The Pistons are averaging 111.7 points, 42.9 rebounds, 25.5 assists, 9.3 steals and 5.4 blocks while shooting 46.9% from the field and 79.7% from the free-throw line. The opposition have averaged 108.0 points and 39.8 rebounds per contest.
Cade Cunningham is averaging 23.7 points and 8.3 assists, while Jalen Duren averages 8.3 rebounds and Duncan Robinson 3.4 (50.7%) 3-pointers made.
Philadelphia 76ers – Last 10 Games
The Sixers have won 6 and lost 4 of their previous 10 contests. Averaging 108.3 points, 39.8 rebounds, 23.1 assists, 7.0 steals and 3.8 blocks per game while shooting 44.8% from the field and 80.2% from the free-throw line. Their opponents have averaged 110.9 points and 47.2 rebounds.
Tyrese Maxey is averaging 24.4 points and 5.1 assists, while Joel Embiid has an average of 7.0 rebounds and Paul George 2.5 (46.3%) 3-pointers made.
Confirmed Starting Lineups
Detroit Pistons lineup: Cade Cunningham, Paul Reed, Ausar Thompson, John Collins, Duncan Robinson.
Philadelphia 76ers lineup: Tyrese Maxey, Jaylen Brown, Joel Embiid, Dean Wade, Valdez Edgecombe.
Best Bet
We’re not convinced these NBA opponents are cumulatively going to produce enough points in relation to the total line. Therefore, we’re aiming to go Under 226.5 at -105.
Key stats supporting our main match prediction:
The 226.5 line hasn’t been covered in 4 of the last 5 Pistons games on the road.The 226.5 line hasn’t been covered in 7 of the last 10 Pistons games.The 226.5 line hasn’t been covered in 16 of the last 20 Sixers games.The 226.5 line hasn’t been covered in 7 of the last 10 Sixers games.
Our team of expert NBA handicappers track current injuries closely. Combined with recent form, this helps us identify the best value odds. A data-led approach backed by key stats and the latest team news keeps our analysis sharp.
Under 226.5 Probability
The best NBA betting sites imply that our pick has a 51.3% prospect of winning. Based on our in-depth research, we calculate the actual probability to be 55-60%. It is the reason why we are recommending this wager.
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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Oct 25, 00:03). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.
Published 00:03, 25 October 2026
Player Prop Picks
Cade Cunningham (Pistons) has averaged 22.2 points in the past 5 games. It’s anticipated that he might once again fall short of the mark and this Player Points wager is available at -106.
Latest Cade Cunningham Player Prop Odds
Tyrese Maxey (76ers) has failed to cover the 6.5 assists total in 8 of the past 10 games. He might fall short when it comes to covering the Player Assists line and you can get -102 for this prop bet.
Latest Tyrese Maxey Player Prop Odds
Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Correct Score Prediction
A close game could be on the cards. We’ll wager the Pistons to secure a 112-111 win at massive odds and this correct score pick should hopefully be a fun one.
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Detroit Pistons vs Philadelphia 76ers Odds
The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.
Sixers Made Favorites by the Books
For this NBA game, the sportsbooks’ Moneyline betting odds mean Philadelphia 76ers are -112 favorites to win and that means a 53% chance of landing a victory. Detroit Pistons are regarded as a long shot to win and you can currently back them at -104.
1.5 is the spread and 226.5 is the total points line. A Total bet relates to the number of points that will be scored overall. There’s the chance to back Under 226.5 at -105.
The good news is that you can access a huge selection of game lines and team props for most contests. The top basketball betting sites have a massive range of pre-game and in-game wagering options.
Betting Lines & Odds
Moneyline

Point Spread

Total Points

Tyrese Maxey Favorite to Get the Most Buckets
Tyrese Maxey is the favorite to hit the most buckets. You can get +106 that he scores Over 26.5 points or -137 that he goes Under.
Player Points
Tyrese Maxey (76ers)

Cade Cunningham (Pistons)

Jaylen Brown (76ers)

LeBron James (76ers)

Player Assists
Cade Cunningham (Pistons)

LeBron James (76ers)

Tyrese Maxey (76ers)

Jaylen Brown (76ers)

Ausar Thompson (Pistons)

VJ Edgecombe (76ers)

Paul Reed Jr (Pistons)

Player Rebounds
Paul Reed Jr (Pistons)

LeBron James (76ers)

Ausar Thompson (Pistons)

Jaylen Brown (76ers)

Micro Betting
An increasing number of basketball bettors are now enjoying micro betting and it’s something which is available on an in-game basis. Wait for the action to start and then wager on something specific to happen.
Live market odds and lines updated regularly. All odds subject to change. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.
Xfinity Mobile Arena
Sixers Record Shows Five Wins in Last Ten at Home
The Sixers have five wins and five losses in the last 10 home games, putting up 107.90 points per contest and giving up 112.20.
The Pistons have five wins and five losses in the last 10 games on the road, averaging 109.90 points on offense and surrendering 106.30 on defense.
Philadelphia 76ers Home Stats
5-5
220.10
107.90
112.20
3
7
Detroit Pistons Away Stats
5-5
216.20
109.90
106.30
3
7
W-L = Wins-Losses
P = Avg. Points
PF = Avg. Points For
PA = Avg. Points Against
O226.5 = Games Over 226.5 Points
U226.5 = Games Under 226.5 Points
Team Stats
Latest regular season and playoff games stats.

Detroit Pistons Stats

Philadelphia 76ers Stats
6 wins and 4 defeats in the last 10 games
5 wins and 5 defeats in the last 10 games on the road
6 wins and 4 defeats in the last 10 games
5 wins and 5 defeats in the last 10 home games
+3.5 Betting Line: Have covered the spread in 6 of the last 10 games
+3.5 Betting Line on the Road: Have covered the spread in 5 of the last 10 games on the road
-3.5 Betting Line: Have covered the spread in 6 of the last 10 games
-3.5 Betting Line at Home: Have covered the spread in 5 of the last 10 home games
Game Totals: An average of 219.70 pts in the previous 10 games
Game Totals on the Road: An average of 216.20 pts in the previous 10 games on the road
Over 226.5: Covered in 3 of the previous 10 games
Over 226.5 on the Road: Covered in 3 of the previous 10 games on the road
Team Totals: Have scored an average of 111.70 pts and allowed 108.00 pts in the last 10 games
Team Totals on the Road: Have scored an average of 109.90 pts and allowed 106.30 pts in the last 10 games on the road
Game Totals: An average of 219.20 pts in the previous 10 games
Game Totals at Home: An average of 220.10 pts in the previous 10 home games
Over 226.5: Covered in 3 of the previous 10 games
Over 226.5 at Home: Covered in 3 of the previous 10 home games
Team Totals: Have scored an average of 108.30 pts and allowed 110.90 pts in the last 10 games
Team Totals at Home: Have scored an average of 107.90 pts and allowed 112.20 pts in the last 10 home games
Last 10 Games
2-Pointers Made: 27.00 (50%)
3-Pointers Made: 13.10 (41%)
Free Throws Made: 18.40 (79.65%)
Rebounds: Total 42.9, Offensive 13.10, Defensive 29.80
Assists: 25.50
Blocks: 5.40
Steals: 9.30
Turnovers : 15.50
Personal Fouls: 23.70
Last 10 Games on the Road
2-Pointers Made: 29.70 (53%)
3-Pointers Made: 11.30 (38%)
Free Throws Made: 16.60 (76.15%)
Rebounds: Total 44.6, Offensive 12.50, Defensive 32.10
Assists: 25.90
Blocks: 7.90
Steals: 9.00
Turnovers : 16.80
Personal Fouls: 23.30
Last 10 Games
2-Pointers Made: 26.40 (53%)
3-Pointers Made: 11.50 (33%)
Free Throws Made: 21.00 (80.15%)
Rebounds: Total 39.8, Offensive 7.70, Defensive 32.10
Assists: 23.10
Blocks: 3.80
Steals: 7.00
Turnovers : 12.20
Personal Fouls: 21.80
Last 10 Home Games
2-Pointers Made: 28.00 (53%)
3-Pointers Made: 11.10 (32%)
Free Throws Made: 18.60 (80.17%)
Rebounds: Total 38, Offensive 9.10, Defensive 28.90
Assists: 22.40
Blocks: 4.50
Steals: 8.40
Turnovers : 11.40
Personal Fouls: 21.30
Expert Analysis by Kyrone Jones
NBA Analyst
About the Analyst
Our basketball previews are produced by a specialised team of analysts, former odds compilers and sports journalists. Picks are research-driven and reviewed for accuracy and editorial consistency under the oversight of our basketball panel and Editor-in-Chief.
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Full Prediction Methodology & Data Sources
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This preview was last updated on Oct 25, 04:38 to reflect the latest team news, injury reports, starting lineups, player rotations, rest and travel factors, key performance metrics and odds movement.
All analysis is produced by professional analysts, supported by proprietary internal models, advanced performance metrics and reviewed by our Basketball Editorial Betting Panel for accuracy and consistency.
Historical performance for our game predictions is tracked and updated regularly for transparency.
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