The Portland Trail Blazers face the Minnesota Timberwolves at Moda Center on Wednesday, October 22, 2025. The game, the first of the 2025-26 season for both teams, tips at 10 p.m. ET on KUNP and FDSN.
The Timberwolves head into their game as a 2.5-point favorite against the Trail Blazers. The point total for the game is set at 219.5.
Timberwolves vs. Trail Blazers betting odds
NBA odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 3:29 a.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Spread: Minnesota -2.5Total: 219.5Moneyline: Minnesota -151, Portland +126
Timberwolves at Trail Blazers odds, spread, & morePredictionPick ATS: Timberwolves (- 2.5)Pick OU:
Over (219.5)Prediction:
Timberwolves 115 – Trail Blazers 109MoneylineThe Timberwolves won 40 of the 63 games they were listed as the moneyline favorite last season (63.5%).When playing as a moneyline favorite with odds of -151 or shorter last year, Minnesota had a record of 33-20 (62.3%).Based on this matchup’s moneyline, the Timberwolves’ implied win probability is 60.2%.Last season, Portland won 26 out of the 69 games, or 37.7%, in which it was the underdog.Last season, the Trail Blazers won 20 of their 60 games, or 33.3%, when they were an underdog by at least +126 on the moneyline.The implied probability of a win by Portland, based on the moneyline, is 44.2%.Against the spreadLast year, the 114.3 points per game the Timberwolves recorded were only 0.4 more points than the Trail Blazers allowed (113.9).Minnesota had a 27-17 record against the spread and a 33-11 record overall last season when scoring more than 113.9 points.Portland went 33-12 against the spread and 27-18 overall when it scored more than 109.3 points last season.Minnesota’s record was 26-16 against the spread and 33-9 overall when it allowed fewer than 110.9 points last season.Last season, the Timberwolves were at the 13th spot in the NBA’s scoring charts (114.3 PPG), while the Trail Blazers allowed the 15th-fewest points per game (113.9) in the league.Portland’s squad was the 22nd-ranked scoring team (110.9 PPG) in the NBA a season ago, while Minnesota ranked fifth in terms of allowing points per game (109.3).The Timberwolves out-scored their opponents by a total of 410 points last season (5.0 points per game on average), and opponents of the Trail Blazers out-scored them by 244 more points on the year (3.0 per game).Over/UnderThe average implied total for Minnesota last season was 114.5 points, 3.5 more points than its implied total of 111 points in Wednesday’s game.Last season, Minnesota put up more than 111 points in 48 games.The 116.5-point average implied total last season for Portland is 7.5 more points than the team’s 109-point implied total in this matchup.How to watch Timberwolves vs. Trail BlazersGame day: Wednesday, October 22, 2025Game time: 10 p.m. ETLocation: Portland, OregonArena: Moda CenterTV channel: FanDuel Sports Network Midwest – IowaLive stream: Watch this game on Fubo