The Detroit Pistons kick off the regular season on the road against the Chicago Bulls at the United Center.

Detroit enters off a breakthrough 44–38 season and a dominant head-to-head edge over Chicago last season. Meanwhile, the Bulls are aiming to re-establish themselves after finishing outside the playoffs in 2025 and face early setbacks with key injuries. With momentum tilted toward Detroit and Chicago’s depth in question, the Pistons hold a clear edge in this season opener.

Detroit leans on its star Cade Cunningham, interior force Jalen Duren, and wings like Ausar Thompson to sustain last season’s progress. Their transition offense and rebounding make them potent, and they’ll focus on maintaining that edge while starters settle early.

Chicago, meanwhile, is retooling around Nikola Vučević, Ayo Dosunmu, and the core of newly developing wings. However, they will be without Zach Collins for at least four weeks following wrist surgery, and guard Coby White remains out for the start of the season. The Bulls must rely on youth and depth to bridge the gap while their veteran support recovers.

Predictions

Detroit has the clear edge with a deeper, healthier roster with playoff experience. With White out, the Bulls have a firepower disadvantage.

Prediction: Pistons 112, Bulls 105

Injury Report

Detroit Pistons

Jaden Ivey — Out (right knee surgery)

Marcus Sasser — Doubtful (right hip impingement)

Chicago Bulls

Coby White — Out (right calf strain)

Zach Collins — Out (left wrist fracture)

How to Watch Detroit Pistons vs. Chicago Bulls

Tip-off for tonight’s Detroit Pistons vs. Chicago Bulls game is set for 8:10 PM Eastern / 7:10 PM Central at United Center in Chicago.

The game airs locally on CHSN and FanDuel Sports Network Detroit (FDSN-D). Fans in Detroit without access to FDSN-Detroit can purchase a standalone subscription here on Amazon to catch their local live sports action.

Out-of-market viewers can stream the game on NBA League Pass, available for $16.99/month or $109.99 for the full season when purchased directly from the NBA website.

Amazon Prime Video offers some discounts as well as ways to watch for free here. League Pass subscriptions start at $12.74 for the first two months on Amazon (then $16.99/month) — and that includes NBA TV.

Fans can also choose a Team Pass to follow one team’s games for $13.99 per month — or watch tonight’s game free with a 7-day trial.

Detroit Pistons vs. Chicago Bulls

Date: Wednesday, October 22, 2025

Time: 8:10 PM Eastern / 7:10 PM Central

Venue: United Center, Chicago, Illinois

TV: FanDuel Sports Network Detroit, CHSN

Streaming: NBA League Pass (out-of-market)