The Minnesota Timberwolves (2-2) hit the court against the Los Angeles Lakers (2-2) as 6.5-point favorites on Wednesday, October 29, 2025 at 9:30 p.m. ET on ESPN, FDSN, and SportsNet LA.
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Timberwolves vs. Lakers Predictions for Wednesday
Our computer projections model for this matchup predicts a final result of Timberwolves 118, Lakers 117.
Moneyline Pick: Timberwolves (-261)
Total Pick: Over 225 (computer predicts 234.8 points)
Pick ATS: Lakers (+6.5)
Recent Timberwolves vs. Lakers Matchups
Timberwolves 2024-25 Betting Trends
Minnesota beat the spread 39 times in 82 games last year.
As 6.5-point favorites or more, the Timberwolves went 15-19 against the spread last year.
Minnesota had 44 of its 82 games hit the over last season.
The Timberwolves finished with a 40-23 record in games they were favored on the moneyline last season (winning 63.5% of those games).
In games it played as a moneyline favorite with odds of -261 or shorter last year, Minnesota had a record of 23-10 (69.7%).
Lakers 2024-25 Betting Trends
Los Angeles compiled a 45-36-1 record against the spread last year.
Against the spread, as underdogs of 6.5 points or greater, the Lakers went 6-5 last year.
A total of 41 of Los Angeles’ games last season went over the point total.
Last season, the Lakers won 15 out of the 33 games, or 45.5%, in which they were the underdog.
Los Angeles had a record of 3-5 when it was set as the underdog by +211 or more by oddsmakers last season.
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Timberwolves vs. Lakers Injury Report
Timberwolves
Timberwolves:
Robert Dillingham: Day-To-Day (Nasal),
Anthony Edwards: Out (Hamstring)
Lakers
Lakers:
Maxi Kleber: Out (Oblique),
LeBron James: Out (Nerve),
Adou Thiero: Out (Knee),
Luka Doncic: Out (Knee / Finger),
Marcus Smart: Day-To-Day (Quadricep),
Gabe Vincent: Out (Ankle),
Jaxson Hayes: Day-To-Day (Knee)
Timberwolves vs. Lakers Game Time and TV Channel
Game day: Wednesday, October 29, 2025
Game time: 9:30 p.m. ET
TV channel: ESPN, FDSN, and SportsNet LA
Location: Minneapolis, Minnesota
Arena: Target Center
Live stream: Watch this game on Fubo (Regional restrictions may apply)
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