The Detroit Pistons (4-2) face the Memphis Grizzlies (3-4) Monday with tip-off at FedExForum in Memphis, Tennessee, set for 9:30 p.m. ET. Let’s analyze BetMGM Sportsbook’s NBA odds around the Pistons vs. Grizzlies odds and make our expert NBA picks and predictions for the best bets.

2024-25 season series: Grizzlies won 2-0

The Pistons made it 2 straight wins with a 122-110 victory over the Dallas Mavericks Saturday night. They easily covered as 7.5-point home favorites with the Over (227.5) cashing. Detroit completely owned the paint, outscoring Dallas 72-26. C Jalen Duren led the way with 33 points and 10 rebounds, while G Cade Cunningham added 21 points and 18 assists.

Memphis dropped its second straight game Sunday, losing 117-104 to the Toronto Raptors. They failed to cover as a 4.5-point road underdog as the under (238.5) hit. F Jaren Jackson Jr. led the Grizzlies with 20 points and 9 rebounds, while C Jock Landale and G Vince Williams Jr. each contributed 14 points in the loss.

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Pistons at Grizzlies odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 11:47 p.m. ET.

Moneyline (ML): Pistons -160 (bet $160 to win $100) | Grizzlies +135 (bet $100 to win $135)Against the spread (ATS): Pistons -3.5 (-110) | Grizzlies +3.5 (-110)Over/Under (O/U): 236.5 (O: -110 | U: -110)Pistons at Grizzlies key injuries

Pistons

F Tobias Harris (ankle) questionableG Marcus Sasser (hip) out

Grizzlies

F Brandon Clarke (knee) outC Zach Edey (ankle) outG Ty Jerome (calf) outG Scotty Pippen Jr.. (toe) out

For most recent updates: Official NBA injury report.

Pistons at Grizzlies picks and predictionsPrediction

Pistons 119, Grizzlies 114

PASS.

I’ve got the Pistons (-160) going on the road and getting a win Monday night, but I’ll take my wager to the spread with better odds.

BET PISTONS -3.5 (-110).

Detroit enters Monday’s matchup as the more consistent and better-rested team — and that’s reason enough to back the Pistons -3.5. The Grizzlies have lost 3 of their last 4 and failed to cover in 4 straight, while the Pistons have won 4 of 5, covering in every victory. Detroit just handled Dallas convincingly and carries strong momentum into Memphis.

The Pistons’ defensive intensity is a key separator. They rank fifth in the NBA in rebounds per game (48.3) and lead the league in blocked shots (7 per game), anchored by Duren’s dominance in the paint. That presence limits second-chance opportunities — a major problem for a Memphis team shooting just 32.7% from 3, ranking 25th in the league.

Even with G Ja Morant expected to return from suspension, Memphis remains shorthanded, missing 4 key players. Meanwhile, Detroit’s depth and physicality should shine through, even if Harris sits. The Grizzlies’ inconsistency and poor perimeter shooting make it tough to trust them, especially against a tough, disciplined Detroit team that thrives on defense and transition play. Back the Pistons to stay hot and cover on the road.

BET UNDER 236.5 (-110).

The Under has cashed in 4 of the last 6 meetings between these teams, and the Grizzlies have gone under in 3 straight and 4 of their last 5. While Detroit has leaned slightly Over lately, none of those totals topped 230. Neither offense is explosive, both ranking middle of the pack in scoring. Expect a slower, grind-it-out game — take the Under.

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