The Cleveland Cavaliers (4-3) play the Philadelphia 76ers (5-2) on Wednesday, November 5, 2025 at 7 p.m. ET on FDSOH and NBCS-PH. For same-game parlay picks, check out the piece below.
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Winning the spread, total and Tyrese Maxey under 30.5 PTS parlay for the Cavaliers-76ers game earns $55.43 on a $10 bet using the computer picks below. Curious how each of those bets looks? Continue scrolling to learn more.
NBA odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 4:16 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
76ers vs. Cavaliers spread pickFavorite: Cavaliers (-10.5)Pick ATS: 76ers +10.5 (Projected score: Cavaliers 118, 76ers 117)Cleveland has posted two wins against the spread this year.The Cavaliers are winless ATS (0-1) when playing as at least 10.5-point favorites this season.Philadelphia is 5-2-0 against the spread this year.76ers vs. Cavaliers total pickTotal: 235.5Pick OU: Under 235.5 (Projecting 234.5 total points)Cleveland and its opponents have scored more than 235.5 points — this matchup’s over/under — only once this year.Philadelphia’s games have gone over 235.5 points in three of seven chances this season.Cavaliers games have had an average of 232.4 points this season, 3.1 fewer than Wednesday’s over/under.The 235.5-point over/under for this game is 1.0 points below the 234.5 points per game average total in 76ers games this season.Tyrese Maxey points propPoints prop: OU 29.5Pick: Under (Projecting 30.1 points)Tyrese Maxey’s 34.4 points per game are 4.9 points more than Wednesday’s over/under.Maxey has gone over five times on a points prop this season (in seven opportunities).76ers vs. Cavaliers game info